Showing results for G. Buonaccorsi

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Experimentally‐derived functional form for a population‐averaged high‐temporal‐resolution arterial input function for dynamic contrast‐enhanced MRI

…, A Macdonald, GA Buonaccorsi… - … in Medicine: An …, 2006 - Wiley Online Library
Rapid T 1 ‐weighted 3D spoiled gradient‐echo (GRE) data sets were acquired in the
abdomen of 23 cancer patients during a total of 113 separate visits to allow dynamic contrast‐…

Photosensitisation and photodynamic therapy of oesophageal, duodenal, and colorectal tumours using 5 aminolaevulinic acid induced protoporphyrin IX--a pilot study …

J Regula, AJ MacRobert, A Gorchein, GA Buonaccorsi… - Gut, 1995 - gut.bmj.com
… duodenal tumours,17 200 counts/pixel corresponds to about 10 ,ug/g of protoporphyrin IX
… 28 Shimizu Y, Ida S, Naruto H, Urata G. Excretion of porphyrins in urine and bile after the …

Photodynamic therapy using 5‐aminolevulinic acid for premalignant and malignant lesions of the oral cavity

…, C Hopper, PM Speight, G Buonaccorsi… - … Journal of the …, 1996 - Wiley Online Library
BACKGROUND Premalignant changes in the mouth, which are often widespread, are frequently
excised or vaporized, whereas cancers are treated by excision or radiotherapy, both of …

Quantifying antivascular effects of monoclonal antibodies to vascular endothelial growth factor: insights from imaging

…, X Wu, TC Cao, S Ross, GA Buonaccorsi… - Clinical Cancer …, 2009 - AACR
Purpose: Little is known concerning the onset, duration, and magnitude of direct therapeutic
effects of anti–vascular endothelial growth factor (VEGF) therapies. Such knowledge would …

Quantifying spatial heterogeneity in dynamic contrast‐enhanced MRI parameter maps

…, JPB O'Connor, GA Buonaccorsi… - … in Medicine: An …, 2009 - Wiley Online Library
Dynamic contrast‐enhanced MRI is becoming a standard tool for imaging‐based trials of
anti‐vascular/angiogenic agents in cancer. So far, however, biomarkers derived from DCE‐MRI …

[HTML][HTML] DCE-MRI biomarkers of tumour heterogeneity predict CRC liver metastasis shrinkage following bevacizumab and FOLFOX-6

…, C Roberts, GA Buonaccorsi, G Thompson… - British journal of …, 2011 - nature.com
Background: There is limited evidence that imaging biomarkers can predict subsequent
response to therapy. Such prognostic and/or predictive biomarkers would facilitate development …

Preliminary study of oxygen-enhanced longitudinal relaxation in MRI: a potential novel biomarker of oxygenation changes in solid tumors

…, Y Watson, GC Jayson, GA Buonaccorsi… - International Journal of …, 2009 - Elsevier
PURPOSE: There is considerable interest in developing non-invasive methods of mapping
tumor hypoxia. Changes in tissue oxygen concentration produce proportional changes in the …

Phase I Evaluation of a Fully Human Anti–αv Integrin Monoclonal Antibody (CNTO 95) in Patients with Advanced Solid Tumors

…, A Jackson, PJ Julyan, C Roberts, GA Buonaccorsi… - Clinical Cancer …, 2007 - AACR
Purpose: A fully human monoclonal antibody to anti–α v integrins (CNTO 95) has been shown
to inhibit angiogenesis and tumor growth in preclinical studies. We assessed the safety …

Photodynamic therapy using mTHPC for malignant disease in the oral cavity

…, PM Speight, GA Buonaccorsi… - … journal of cancer, 1997 - Wiley Online Library
Photodynamic therapy (PDT) produces local tumor necrosis, on activation of a previously
administered sensitizer with non‐thermal light of an appropriate wavelength. It is attractive for …

Laser therapy for breast cancer: MR imaging and histopathologic correlation.

…, A Wotherspoon, M Paley, G Buonaccorsi… - Radiology, 1996 - pubs.rsna.org
PURPOSE: To investigate magnetic resonance (MR) imaging guidance of interstitial laser
photocoagulation to treat primary breast cancer. MATERIALS AND METHODS: Twenty female …