Organs-on-chips (OoCs) are systems containing engineered or natural miniature tissues
grown inside microfluidic chips. To better mimic human physiology, the chips are designed to …

Pancreatic ductal adenocarcinoma (PDA) is a lethal disease. Overall survival is typically 6
months from diagnosis 1. Numerous phase 3 trials of agents effective in other malignancies …

Immune evasion is a major obstacle for cancer treatment. Common mechanisms of evasion
include impaired antigen presentation caused by mutations or loss of heterozygosity of the …

… For in vitro RNA pull-down, TINCR, LacZ and ANCR mRNAs were labelled with biotin-16-UTP
(GE Healthcare) during in vitro transcription reaction according to the manufacturer’s …

Chronic pancreatitis is a well-known risk factor for pancreatic ductal adenocarcinoma (PDA)
development in humans, and inflammation promotes PDA initiation and progression in …

Fibrosis compromises pancreatic ductal carcinoma (PDAC) treatment and contributes to
patient mortality, yet antistromal therapies are controversial. We found that human PDACs with …

Long noncoding RNAs (lncRNAs) regulate diverse processes, yet a potential role for
lncRNAs in maintaining the undifferentiated state in somatic tissue progenitor cells remains …

… Building on the work completed by Kim et al, 14 the purpose of this study was to complete
the chart verification of all patients who received at least 1 code for HS in a large patient care …

Aluminum 5083 powder was mechanically milled under liquid nitrogen to achieve a nanocrystalline
grain size in the range of 20 to 30 nm. The powder was subsequently sprayed using …

Osteosarcoma is treated with a chemotherapy regimen established 30 years ago. Although
osteosarcoma is genomically complex, we hypothesized that tumor-specific dependencies …