Rapid, label-free detection of brain tumors with stimulated Raman scattering microscopy
…, NYR Agar, GS Young, C Spino, S Santagata… - Science translational …, 2013 - science.org
Surgery is an essential component in the treatment of brain tumors. However, delineating
tumor from normal brain remains a major challenge. We describe the use of stimulated Raman …
tumor from normal brain remains a major challenge. We describe the use of stimulated Raman …
Diffusion-weighted and fluid-attenuated inversion recovery imaging in Creutzfeldt-Jakob disease: high sensitivity and specificity for diagnosis
GS Young, MD Geschwind… - American Journal …, 2005 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Abnormalities on diffusion-weighted images (DWIs) and
fluid-attenuated inversion recovery (FLAIR) images are reported in Creutzfeldt-Jakob disease (…
fluid-attenuated inversion recovery (FLAIR) images are reported in Creutzfeldt-Jakob disease (…
Chemically-selective imaging of brain structures with CARS microscopy
We demonstrate the use of coherent anti-Stokes Raman scattering (CARS) microscopy to
image brain structure and pathology ex vivo. Although non-invasive clinical brain imaging with …
image brain structure and pathology ex vivo. Although non-invasive clinical brain imaging with …
Advanced MRI of adult brain tumors
GS Young - Neurologic clinics, 2007 - Elsevier
This article is intended to provide clinical neurologists with an overview of the major techniques
of advanced MRI of brain tumor: diffusion-weighted imaging, perfusion-weighted imaging…
of advanced MRI of brain tumor: diffusion-weighted imaging, perfusion-weighted imaging…
Apparent diffusion coefficient histogram analysis stratifies progression-free and overall survival in patients with recurrent GBM treated with bevacizumab: a multi-center …
…, VK Puduvalli, J Wu, WKA Yung, GS Young… - Journal of neuro …, 2012 - Springer
We have tested the predictive value of apparent diffusion coefficient (ADC) histogram analysis
in stratifying progression-free survival (PFS) and overall survival (OS) in bevacizumab-…
in stratifying progression-free survival (PFS) and overall survival (OS) in bevacizumab-…
[HTML][HTML] Multicolored stain-free histopathology with coherent Raman imaging
Conventional histopathology with hematoxylin & eosin (H&E) has been the gold standard
for histopathological diagnosis of a wide range of diseases. However, it is not performed in …
for histopathological diagnosis of a wide range of diseases. However, it is not performed in …
Support vector machine multiparametric MRI identification of pseudoprogression from tumor recurrence in patients with resected glioblastoma
Purpose To automatically differentiate radiation necrosis from recurrent tumor at high spatial
resolution using multiparametric MRI features. Materials and Methods MRI data retrieved …
resolution using multiparametric MRI features. Materials and Methods MRI data retrieved …
[HTML][HTML] Buparlisib in patients with recurrent glioblastoma harboring phosphatidylinositol 3-kinase pathway activation: an open-label, multicenter, multi-arm, phase II …
PURPOSE Phosphatidylinositol 3-kinase (PI3K) signaling is highly active in glioblastomas.
We assessed pharmacokinetics, pharmacodynamics, and efficacy of the pan-PI3K inhibitor …
We assessed pharmacokinetics, pharmacodynamics, and efficacy of the pan-PI3K inhibitor …
Deep‐learning detection of cancer metastases to the brain on MRI
Background Approximately one‐fourth of all cancer metastases are found in the brain. MRI
is the primary technique for detection of brain metastasis, planning of radiotherapy, and the …
is the primary technique for detection of brain metastasis, planning of radiotherapy, and the …
Automated brain tumor segmentation using spatial accuracy-weighted hidden Markov Random Field
A variety of algorithms have been proposed for brain tumor segmentation from multi-channel
sequences, however, most of them require isotropic or pseudo-isotropic resolution of the …
sequences, however, most of them require isotropic or pseudo-isotropic resolution of the …