[HTML][HTML] Management of neuropsychiatric systemic lupus erythematosus: current approaches and future perspectives

…, EJ Zirkzee, TW Huizinga, GM Steup-Beekman - Drugs, 2016 - Springer
Neuropsychiatric systemic lupus erythematosus (NPSLE) is a generic definition referring to
a series of neurological and psychiatric symptoms directly related to systemic lupus …

Diagnosis and management of the antiphospholipid syndrome

D Cohen, SP Berger, GM Steup-Beekman… - Bmj, 2010 - bmj.com
Antiphospholipid syndrome was first described 27 years ago in patients with systemic lupus
erythematosus (SLE) and positive anticardiolipin antibodies, who presented with a clotting …

Brain histopathology in patients with systemic lupus erythematosus: identification of lesions associated with clinical neuropsychiatric lupus syndromes and the role of …

…, EC Rijnink, RJA Nabuurs, GM Steup-Beekman… - …, 2016 - academic.oup.com
Objectives. Neuropsychiatric (NP) involvement is a poorly understood manifestation of SLE.
We studied post-mortem histopathology in relation to clinical NPSLE syndromes and …

Potential for glomerular C4d as an indicator of thrombotic microangiopathy in lupus nephritis

…, GM SteupBeekman… - … : Official Journal of …, 2008 - Wiley Online Library
Objective In patients with systemic lupus erythematosus (SLE) and lupus nephritis, the presence
of antiphospholipid antibodies (aPL) is considered to be an indication of increased risk …

Prospective study of clinical phenotypes in neuropsychiatric systemic lupus erythematosus; multidisciplinary approach to diagnosis and therapy

EJM Zirkzee, GM Steup-Beekman, EL Bollen… - The Journal of …, 2012 - jrheum.org
Objective. To describe clinical phenotypes in neuropsychiatric systemic lupus erythematosus
(NPSLE). Methods. Data were prospectively collected in the Leiden NPSLE referral clinic, …

Neuropsychiatric manifestations in patients with systemic lupus erythematosus: epidemiology and radiology pointing to an immune-mediated cause

GM Steup-Beekman, EJM Zirkzee, D Cohen… - Annals of the …, 2013 - ard.bmj.com
Background Different pathogenetic pathways have been proposed for neuropsychiatric (NP)
manifestations in systemic lupus erythematosus (SLE). Objective To describe the patient …

Clinical and radiological outcomes of 5-year drug-free remission-steered treatment in patients with early arthritis: IMPROVED study

…, AJ Peeters, GM Steup-Beekman… - Annals of the …, 2018 - ard.bmj.com
Objectives To determine the 5-year outcomes of early remission induction therapy followed
by targeted treatment aimed at drug-free remission (DFR) in patients with early arthritis. …

Glial and axonal changes in systemic lupus erythematosus measured with diffusion of intracellular metabolites

…, F Branzoli, ET Wood, GM Steup-Beekman… - Brain, 2016 - academic.oup.com
Systemic lupus erythematosus is an inflammatory autoimmune disease with multi-organ
involvement. Central nervous system involvement in systemic lupus erythematosus is common …

[HTML][HTML] Antibodies against carbamylated proteins and cyclic citrullinated peptides in systemic lupus erythematosus: results from two well-defined European cohorts

…, T Skogh, C Magro-Checa, GM Steup-Beekman… - Arthritis research & …, 2016 - Springer
Background Articular manifestations are common in systemic lupus erythematosus (SLE)
whereas erosive disease is not. Antibodies to cyclic citrullinated peptide (anti-CCP) are …

Value of multidisciplinary reassessment in attribution of neuropsychiatric events to systemic lupus erythematosus: prospective data from the Leiden NPSLE cohort

…, TWJ Huizinga, GM Steup-Beekman - …, 2017 - academic.oup.com
Objective To determine the contribution of reassessment in the attribution process of
neuropsychiatric (NP) events to SLE or other aetiologies in a large, prospective and …