User profiles for H. Khosravani

Houman Khosravani, MD PhD FRCPC

- Verified email at ccmd.io - Cited by 4785

Hamid Reza Khosravani

- Verified email at ualg.pt - Cited by 475

Protected code stroke: hyperacute stroke management during the coronavirus disease 2019 (COVID-19) pandemic

H Khosravani, P Rajendram, L Notario, MG Chapman… - Stroke, 2020 - Am Heart Assoc
… Dr Khosravani conceived the main conceptual idea of a protected code stroke and wrote
the manuscript with support from Drs Rajendram, Chapman, and Menon and Notario. …

Proposed consensus definitions for new‐onset refractory status epilepticus (NORSE), febrile infection‐related epilepsy syndrome (FIRES), and related conditions

…, NS Abend, EJ Gilmore, C Hahn, H Khosravani… - …, 2018 - Wiley Online Library
We convened an international group of experts to standardize definitions of New‐Onset
Refractory Status Epilepticus (NORSE), Febrile Infection‐Related Epilepsy Syndrome (FIRES), …

Voltage-gated calcium channels and idiopathic generalized epilepsies

H Khosravani, GW Zamponi - Physiological reviews, 2006 - journals.physiology.org
… This T-type-mediated potential can interact with other active currents (eg, I h ) to
modulate neuronal output between nonoscillatory and oscillatory modes that have different …

Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised …

…, SB Coutts, S Thirunavukkarasu, H Khosravani… - The Lancet, 2022 - thelancet.com
Background Intravenous thrombolysis with alteplase bolus followed by infusion is a global
standard of care for patients with acute ischaemic stroke. We aimed to determine whether …

Prion protein attenuates excitotoxicity by inhibiting NMDA receptors

H Khosravani, Y Zhang, S Tsutsui, S Hameed… - The Journal of cell …, 2008 - rupress.org
… maintained at that temperature for 2–5 h for subsequent electrophysiological recordings.
All slices were allowed a minimum of 1 h of recovery before experimentation. Tissue samples …

[HTML][HTML] Occurrence and adverse effect on outcome of hyperlactatemia in the critically ill

H Khosravani, R Shahpori, HT Stelfox, AW Kirkpatrick… - Critical care, 2009 - Springer
Introduction Hyperlactatemia is frequent in critically ill patients and is often used as a marker
of adverse outcome. However, studies to date have focused on selected intensive care unit (…

[HTML][HTML] Gating effects of mutations in the Cav3. 2 T-type calcium channel associated with childhood absence epilepsy

H Khosravani, C Altier, B Simms, KS Hamming… - Journal of Biological …, 2004 - ASBMB
… Houman Khosravani Houman Khosravani … Cells were transferred to 28 C 24 h after
transfection, and recordings were conducted 2 days later. …

Extended spectrum of idiopathic generalized epilepsies associated with CACNA1H functional variants

SE Heron, H Khosravani, D Varela… - Annals of Neurology …, 2007 - Wiley Online Library
Objective The relationship between genetic variation in the T‐type calcium channel gene
CACNA1H and childhood absence epilepsy is well established. The purpose of this study was …

ORL1 receptor–mediated internalization of N-type calcium channels

C Altier, H Khosravani, RM Evans, S Hameed… - Nature …, 2006 - nature.com
The inhibition of N-type calcium channels by opioid receptor like receptor 1 (ORL1) is a key
mechanism for controlling the transmission of nociceptive signals. We recently reported that …

[HTML][HTML] Specific lipids supply critical negative spontaneous curvature—An essential component of native Ca2+-triggered membrane fusion

…, T Rogasevskaia, DM Brandman, H Khosravani… - Biophysical journal, 2008 - cell.com
The Ca 2+ -triggered merger of two apposed membranes is the defining step of regulated
exocytosis. CHOL is required at critical levels in secretory vesicle membranes to enable …