Protected code stroke: hyperacute stroke management during the coronavirus disease 2019 (COVID-19) pandemic
… Dr Khosravani conceived the main conceptual idea of a protected code stroke and wrote
the manuscript with support from Drs Rajendram, Chapman, and Menon and Notario. …
the manuscript with support from Drs Rajendram, Chapman, and Menon and Notario. …
Proposed consensus definitions for new‐onset refractory status epilepticus (NORSE), febrile infection‐related epilepsy syndrome (FIRES), and related conditions
We convened an international group of experts to standardize definitions of New‐Onset
Refractory Status Epilepticus (NORSE), Febrile Infection‐Related Epilepsy Syndrome (FIRES), …
Refractory Status Epilepticus (NORSE), Febrile Infection‐Related Epilepsy Syndrome (FIRES), …
Voltage-gated calcium channels and idiopathic generalized epilepsies
H Khosravani, GW Zamponi - Physiological reviews, 2006 - journals.physiology.org
… This T-type-mediated potential can interact with other active currents (eg, I h ) to
modulate neuronal output between nonoscillatory and oscillatory modes that have different …
modulate neuronal output between nonoscillatory and oscillatory modes that have different …
Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised …
Background Intravenous thrombolysis with alteplase bolus followed by infusion is a global
standard of care for patients with acute ischaemic stroke. We aimed to determine whether …
standard of care for patients with acute ischaemic stroke. We aimed to determine whether …
Prion protein attenuates excitotoxicity by inhibiting NMDA receptors
H Khosravani, Y Zhang, S Tsutsui, S Hameed… - The Journal of cell …, 2008 - rupress.org
… maintained at that temperature for 2–5 h for subsequent electrophysiological recordings.
All slices were allowed a minimum of 1 h of recovery before experimentation. Tissue samples …
All slices were allowed a minimum of 1 h of recovery before experimentation. Tissue samples …
[HTML][HTML] Occurrence and adverse effect on outcome of hyperlactatemia in the critically ill
H Khosravani, R Shahpori, HT Stelfox, AW Kirkpatrick… - Critical care, 2009 - Springer
Introduction Hyperlactatemia is frequent in critically ill patients and is often used as a marker
of adverse outcome. However, studies to date have focused on selected intensive care unit (…
of adverse outcome. However, studies to date have focused on selected intensive care unit (…
[HTML][HTML] Gating effects of mutations in the Cav3. 2 T-type calcium channel associated with childhood absence epilepsy
H Khosravani, C Altier, B Simms, KS Hamming… - Journal of Biological …, 2004 - ASBMB
… Houman Khosravani Houman Khosravani … Cells were transferred to 28 C 24 h after
transfection, and recordings were conducted 2 days later. …
transfection, and recordings were conducted 2 days later. …
Extended spectrum of idiopathic generalized epilepsies associated with CACNA1H functional variants
Objective The relationship between genetic variation in the T‐type calcium channel gene
CACNA1H and childhood absence epilepsy is well established. The purpose of this study was …
CACNA1H and childhood absence epilepsy is well established. The purpose of this study was …
ORL1 receptor–mediated internalization of N-type calcium channels
C Altier, H Khosravani, RM Evans, S Hameed… - Nature …, 2006 - nature.com
The inhibition of N-type calcium channels by opioid receptor like receptor 1 (ORL1) is a key
mechanism for controlling the transmission of nociceptive signals. We recently reported that …
mechanism for controlling the transmission of nociceptive signals. We recently reported that …
[HTML][HTML] Specific lipids supply critical negative spontaneous curvature—An essential component of native Ca2+-triggered membrane fusion
…, T Rogasevskaia, DM Brandman, H Khosravani… - Biophysical journal, 2008 - cell.com
The Ca 2+ -triggered merger of two apposed membranes is the defining step of regulated
exocytosis. CHOL is required at critical levels in secretory vesicle membranes to enable …
exocytosis. CHOL is required at critical levels in secretory vesicle membranes to enable …