Background: Acute disseminated encephalomyelitis (ADEM) is typically a monophasic
demyelinating disorder. However, a clinical presentation consistent with ADEM can also be the …

Assessment of the progression of myelin and myelination has been revolutionized in the era
of MR imaging. Earlier imaging modalities such as ultrasonography and computed …

Background Multiple sclerosis (MS) diagnostic criteria incorporate MRI features that can be
used to predict later diagnosis of MS in adults with acute CNS demyelination. To identify MRI …

Background: MRI diagnostic criteria have not yet been adopted for pediatric multiple sclerosis
(MS). MRI plays a pivotal role in supporting the diagnosis of MS in adults. We sought to …

Objective: The diagnosis of multiple sclerosis (MS) rests on confirmation of central nervous
system inflammatory disease that is disseminated in space and time, as evidenced clinically …

Objective: To review our multicenter experience with cyclophosphamide in the treatment of
children with multiple sclerosis (MS). Methods: Retrospective chart review of children with MS …

… Branson, MBBS, M. Mallar Chakravarty, PhD, Kenneth J. Poskitt, MDCM, Anne Synnes, …
Branson report no disclosures relevant to the manuscript. M. Chakravarty has … Branson, MBBS …

Background MRI and laboratory features have been incorporated into international diagnostic
criteria for multiple sclerosis. We assessed the pattern of MRI lesions and contributions of …

Background: Brain injury, impaired brain growth, and long-term neurodevelopmental
problems are common in children with transposition of the great arteries. We sought to identify …

The authors collected demographic, clinical, and neuroimaging data prospectively on 38
children with transverse myelitis. One child died during the illness. The female:male ratio was …