Effects of extracranial–intracranial bypass for patients with hemorrhagic moyamoya disease: results of the Japan Adult Moyamoya Trial

…, T Fukui, Y Fukuuchi, T Ohmoto, Y Kuwabara, I Nagata… - Stroke, 2014 - Am Heart Assoc
Background and Purpose— About one half of those who develop adult-onset moyamoya
disease experience intracranial hemorrhage. Despite the extremely high frequency of …

Effect of AT877 on cerebral vasospasm after aneurysmal subarachnoid hemorrhage: results of a prospective placebo-controlled double-blind trial

…, K Sugita, I Saito, T Sasaki, K Takakura, I Nagata… - Journal of …, 1992 - thejns.org
✓ With the cooperation of 60 neurosurgical centers in Japan, a prospective randomized
placebo-controlled double-blind trial of a new calcium antagonist AT877 (hexahydro-1-(5-…

Incidence and clinical features of symptomatic cerebral hyperperfusion syndrome after vascular reconstruction

K Hayashi, N Horie, K Suyama, I Nagata - World neurosurgery, 2012 - Elsevier
BACKGROUND: Vascular reconstructions are the established treatment for ischemic
cerebrovascular disease. Cerebral hyperperfusion syndrome (CHS) is occasionally seen after …

Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia

…, K Iihara, S Takami, I Nagata… - Proceedings of the …, 2001 - National Acad Sciences
Brain subjected to acute ischemic attack caused by an arterial blockage needs immediate
arterial recanalization. However, restoration of cerebral blood flow can cause tissue injury, …

Intracranial hemorrhage associated with cerebral hyperperfusion syndrome following carotid endarterectomy and carotid artery stenting: retrospective review of 4494 …

…, K Hosoda, K Iihara, K Toyoda, C Sakai, I Nagata… - Journal of …, 2007 - thejns.org
Object Intracranial hemorrhage associated with cerebral hyperperfusion syndrome (CHS)
following carotid endarterectomy (CEA) or carotid artery stenting (CAS) is a rare but potentially …

Prevention of rat cerebral aneurysm formation by inhibition of nitric oxide synthase

S Fukuda, N Hashimoto, H Naritomi, I Nagata… - Circulation, 2000 - Am Heart Assoc
Background—Cerebral saccular aneurysm is a major cause of subarachnoid hemorrhage,
one of the cerebrovascular diseases with the highest mortality. The mechanisms underlying …

Nationwide survey of decompressive hemicraniectomy for malignant middle cerebral artery infarction in Japan

K Suyama, N Horie, K Hayashi, I Nagata - World neurosurgery, 2014 - Elsevier
Objective Decompressive hemicraniectomy (DHC) for malignant middle cerebral artery (MCA)
infarction has been shown to reduce mortality and improve functional outcomes in young …

Neuroprotection by MAPK/ERK kinase inhibition with U0126 against oxidative stress in a mouse neuronal cell line and rat primary cultured cortical neurons

T Satoh, D Nakatsuka, Y Watanabe, I Nagata… - Neuroscience …, 2000 - Elsevier
Oxidative stress is implicated in the pathogenesis of neuronal degenerative diseases. Oxidative
stress has been shown to activate extracellular signal-regulated kinases (ERK)1/2. We …

MiR-195, miR-455-3p and miR-10a∗ are implicated in acquired temozolomide resistance in glioblastoma multiforme cells

…, K Suzuki, K Hayashi, T Matsuo, K Kamada, I Nagata… - Cancer letters, 2010 - Elsevier
To identify microRNAs (miRNAs) specifically involved in the acquisition of temozolomide (TMZ)
resistance in glioblastoma multiforme (GBM), we first established a resistant variant, …

Aneurysms of the posterior cerebral artery: retrospective review of surgical treatment

…, H Yokoyama, M Yonekura, I Nagata - Neurologia medico …, 2004 - jstage.jst.go.jp
A series of 10 cases of posterior cerebral artery (PCA) aneurysms were retrospectively
reviewed. There were five men and five women aged 38 to 68 years (mean 57.5 years). Seven …