The role of mutations in epigenetic regulators in myeloid malignancies
AH Shih, O Abdel-Wahab, JP Patel… - Nature Reviews Cancer, 2012 - nature.com
Recent genomic studies have identified novel recurrent somatic mutations in patients with
myeloid malignancies, including myeloproliferative neoplasms (MPNs), myelodysplastic …
myeloid malignancies, including myeloproliferative neoplasms (MPNs), myelodysplastic …
Phyllanthus amarus: ethnomedicinal uses, phytochemistry and pharmacology: a review
JR Patel, P Tripathi, V Sharma, NS Chauhan… - Journal of …, 2011 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Phyllanthus amarus Schum. & Thonn. belongs
to the family Euphorbiaceae is a small herb well known for its medicinal properties and …
to the family Euphorbiaceae is a small herb well known for its medicinal properties and …
Equine herpesviruses 1 (EHV-1) and 4 (EHV-4)–epidemiology, disease and immunoprophylaxis: a brief review
JR Patel, J Heldens - The Veterinary Journal, 2005 - Elsevier
This review concentrates on the epidemiology, latency and pathogenesis of, and the approaches
taken to control infection of horses by equine herpesvirus types 1 (EHV-1) and 4 (EHV-…
taken to control infection of horses by equine herpesvirus types 1 (EHV-1) and 4 (EHV-…
[PDF][PDF] Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
Cancer-associated IDH mutations are characterized by neomorphic enzyme activity and
resultant 2-hydroxyglutarate (2HG) production. Mutational and epigenetic profiling of a large …
resultant 2-hydroxyglutarate (2HG) production. Mutational and epigenetic profiling of a large …
[PDF][PDF] The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting α-ketoglutarate to 2-hydroxyglutarate
PS Ward, J Patel, DR Wise, O Abdel-Wahab… - Cancer cell, 2010 - cell.com
The somatic mutations in cytosolic isocitrate dehydrogenase 1 (IDH1) observed in gliomas
can lead to the production of 2-hydroxyglutarate (2HG). Here, we report that tumor 2HG is …
can lead to the production of 2-hydroxyglutarate (2HG). Here, we report that tumor 2HG is …
[HTML][HTML] Prognostic relevance of integrated genetic profiling in acute myeloid leukemia
JP Patel, M Gönen, ME Figueroa… - … England Journal of …, 2012 - Mass Medical Soc
Background Acute myeloid leukemia (AML) is a heterogeneous disease with respect to
presentation and clinical outcome. The prognostic value of recently identified somatic mutations …
presentation and clinical outcome. The prognostic value of recently identified somatic mutations …
[HTML][HTML] Poverty, inequality and COVID-19: the forgotten vulnerable
JA Patel, FBH Nielsen, AA Badiani, S Assi… - Public …, 2020 - ncbi.nlm.nih.gov
On various occasions, the phrase,‘COVID-19 does not discriminate’has been repeated. This,
however, is a dangerous myth, sidelining the increased vulnerability of those most socially …
however, is a dangerous myth, sidelining the increased vulnerability of those most socially …
[PDF][PDF] Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
Somatic loss-of-function mutations in the ten-eleven translocation 2 (TET2) gene occur in a
significant proportion of patients with myeloid malignancies. Although there are extensive …
significant proportion of patients with myeloid malignancies. Although there are extensive …
Bandgap‐tunable cesium lead halide perovskites with high thermal stability for efficient solar cells
… (J–V) scan efficiency which delivered 5.6% SPO. In Figure 3a,b we show histograms of the
J–… We show the J–V scans and SPO measurement for the champion solar cell in Figure 3c,d. …
J–… We show the J–V scans and SPO measurement for the champion solar cell in Figure 3c,d. …
Perovskite-perovskite tandem photovoltaics with optimized band gaps
We demonstrate four- and two-terminal perovskite-perovskite tandem solar cells with ideally
matched band gaps. We develop an infrared-absorbing 1.2–electron volt band-gap …
matched band gaps. We develop an infrared-absorbing 1.2–electron volt band-gap …