Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

…, SE Arnold, R Barber, T Beach, EH Bigio, JD Bowen… - Nature …, 2011 - nature.com
The Alzheimer Disease Genetics Consortium (ADGC) performed a genome-wide association
study of late-onset Alzheimer disease using a three-stage design consisting of a discovery …

Dementia epidemiology

WA Kukull, JD Bowen - Medical Clinics, 2002 - medical.theclinics.com
Dementia has become one of the leading public health concerns facing our society. The
past few decades have seen remarkable success in treating some acute illnesses and in …

[HTML][HTML] The direct effects of fingolimod in the central nervous system: implications for relapsing multiple sclerosis

SF Hunter, JD Bowen, AT Reder - CNS drugs, 2016 - Springer
Fingolimod, a structural analog of sphingosine derived from fungal metabolites, is a functional
antagonist of the G-protein-coupled sphingosine 1-phosphate (S1P) receptors S1P 1,3,4,5 …

Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older

EB Larson, LI Wang, JD Bowen… - Annals of internal …, 2006 - acpjournals.org
Background: Alzheimer disease and other dementing disorders are major sources of
morbidity and mortality in aging societies. Proven strategies to delay onset or reduce risk for …

[HTML][HTML] Autologous hematopoietic cell transplantation for treatment-refractory relapsing multiple sclerosis: position statement from the American Society for Blood and …

JA Cohen, LE Baldassari, HL Atkins, JD Bowen… - Biology of Blood and …, 2019 - Elsevier
Multiple sclerosis (MS) is a chronic, disabling, immune-mediated, demyelinating and degenerative
disease of the central nervous system. Approved disease-modifying therapies may be …

[BOOK][B] The grammatical structures of English and Spanish

RP Stockwell, JD Bowen, JW Martin - 1965 - books.google.com
This series is designed to provide a detailed account of one of the major problems in the
teaching of a second language—the interference caused by structural differences between the …

[HTML][HTML] Glucose levels and risk of dementia

…, W McCormick, SM McCurry, JD Bowen… - … England Journal of …, 2013 - Mass Medical Soc
Background Diabetes is a risk factor for dementia. It is unknown whether higher glucose
levels increase the risk of dementia in people without diabetes. Methods We used 35,264 …

Dementia and Alzheimer disease incidence: a prospective cohort study

WA Kukull, R Higdon, JD Bowen… - Archives of …, 2002 - jamanetwork.com
Context Age-specific incidence rates for dementia and Alzheimer disease (AD) are important
for research and clinical practice. Incidence estimates for the United States are few and …

Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

…, M Boehringer, T Boerner, R Bonek, JD Bowen… - The Lancet, 2018 - thelancet.com
Background No treatment has consistently shown efficacy in slowing disability progression
in patients with secondary progressive multiple sclerosis (SPMS). We assessed the effect of …

Depressive symptoms and severity of illness in multiple sclerosis: epidemiologic study of a large community sample

…, LE Gibbons, M Sullivan, JD Bowen… - American journal of …, 2002 - Am Psychiatric Assoc
OBJECTIVE: Previous research has shown high prevalence rates of depression in multiple
sclerosis patients seen in specialty clinics. The relationships among depressive symptoms …