The role of the gut–brain axis in alcohol use disorders
J Gorky, J Schwaber - Progress in Neuro-Psychopharmacology and …, 2016 - Elsevier
Neuroimmune and inflammatory processes have been locally associated with the amygdala
in alcohol exposure and withdrawal. We and others have suggested that this inflammation …
in alcohol exposure and withdrawal. We and others have suggested that this inflammation …
[HTML][HTML] Single-cell glia and neuron gene expression in the central amygdala in opioid withdrawal suggests inflammation with correlated gut dysbiosis
…, J Park, A Srivastava, BAS Reyes, J Gorky… - Frontiers in …, 2019 - frontiersin.org
Drug-seeking in opioid dependence is due in part to the severe negative emotion associated
with the withdrawal syndrome. It is well-established that negative emotional states emerge …
with the withdrawal syndrome. It is well-established that negative emotional states emerge …
[PDF][PDF] A comprehensive integrated anatomical and molecular atlas of rat intrinsic cardiac nervous system
We have developed and integrated several technologies including whole-organ imaging
and software development to support an initial precise 3D neuroanatomical mapping and …
and software development to support an initial precise 3D neuroanatomical mapping and …
The impact of lesion in-painting and registration methods on voxel-based morphometry in detecting regional cerebral gray matter atrophy in multiple sclerosis
BACKGROUND AND PURPOSE: VBM has been widely used to study GM atrophy in MS.
MS lesions lead to segmentation and registration errors that may affect the reliability of VBM …
MS lesions lead to segmentation and registration errors that may affect the reliability of VBM …
[HTML][HTML] Investigating the effects of brainstem neuronal adaptation on cardiovascular homeostasis
… f min,j and f max,j represent the firing frequency output range of the jth neuronal subtype or
neuronal population. The variable f input,j … is represented by f midpt,j and reflects the range of …
neuronal population. The variable f input,j … is represented by f midpt,j and reflects the range of …
[HTML][HTML] GutLogo: Agent-based modeling framework to investigate spatial and temporal dynamics in the gut microbiome
C Lin, J Culver, B Weston, E Underhill, J Gorky… - PLoS …, 2018 - journals.plos.org
Knowledge of the spatial and temporal dynamics of the gut microbiome is essential to
understanding the state of human health, as over a hundred diseases have been correlated with …
understanding the state of human health, as over a hundred diseases have been correlated with …
[HTML][HTML] An agent-based model to investigate microbial initiation of Alzheimer's via the olfactory system
…, C Battistoni, R McNulty, F Morales, J Gorky… - Theoretical Biology and …, 2020 - Springer
Background Alzheimer’s disease (AD) is a degenerative brain disease. A novel agent-based
modelling framework was developed in NetLogo 3D to provide fundamental insights into …
modelling framework was developed in NetLogo 3D to provide fundamental insights into …
[HTML][HTML] Conceptualization of a parasympathetic endocrine system
J Gorky, J Schwaber - Frontiers in neuroscience, 2019 - frontiersin.org
We here propose a parasympathetic endocrine system (PES) comprised of circulating peptides
released from secretory cells in the gut, significantly modulated by vagal projections from …
released from secretory cells in the gut, significantly modulated by vagal projections from …
A Physiologically‐Based Pharmacokinetic Model for Targeting Calcitriol‐Conjugated Quantum Dots to Inflammatory Breast Cancer Cells
…, M Wagner, RJ Schaefer, J Gorky… - Clinical and …, 2019 - Wiley Online Library
Quantum dots ( QD s) conjugated with 1,25 dihydroxyvitamin D3 (calcitriol) and Mucin‐1 (
MUC ‐1) antibodies ( SM 3) have been found to target inflammatory breast cancer ( IBC ) …
MUC ‐1) antibodies ( SM 3) have been found to target inflammatory breast cancer ( IBC ) …
[PDF][PDF] Input-output signal processing plasticity of vagal motor neurons in response to cardiac ischemic injury
J Gorky, A Moss, M Balycheva, R Vadigepalli… - Iscience, 2021 - cell.com
Vagal stimulation is emerging as the next frontier in bioelectronic medicine to modulate
peripheral organ health and treat disease. The neuronal molecular phenotypes in the dorsal …
peripheral organ health and treat disease. The neuronal molecular phenotypes in the dorsal …