As covered in the preceding sections, acute renal failure (ARF) is a syndrome associated with
high mortality in humans. Current therapy is limited to supportive measures and preventive …

The transition of AKI to CKD has major clinical significance. As reviewed here, recent studies
show that a subpopulation of dedifferentiated, proliferating tubules recovering from AKI …

Kerr et al (1) in 1972 coined the term “apoptosis,” an ancient Greek word used to describe
the “falling off” of leaves from trees or petals from flowers, referring to the particular …

Importance Severely injured patients experiencing hemorrhagic shock often require massive
transfusion. Earlier transfusion with higher blood product ratios (plasma, platelets, and red …

Background: In animal models, variations in early maternal care are associated with differences
in hypothalamic-pituitary-adrenal (HPA) stress response in the offspring, mediated via …

… incompatible sets of Jrules. So in order to decide whether a proposed system of J-rules is …
"set of conditions that aie necessary and sufficient for a set of J-rules to be right."12 But now the …

Purpose To provide guidance to clinicians regarding therapy for patients with brain
metastases from solid tumors. Methods ASCO convened an Expert Panel and conducted a …

Receptor-interacting protein kinase 3 (RIPK3)-mediated necroptosis is thought to be the
pathophysiologically predominant pathway that leads to regulated necrosis of parenchymal …

Ferrostatin-1 (Fer-1) inhibits ferroptosis, a form of regulated, oxidative, nonapoptotic cell
death. We found that Fer-1 inhibited cell death in cellular models of Huntington’s disease (HD), …

In the following we present material in tabular and graphical form, with the aim to allow the
non-specialist to obtain a realistic estimate of the diffuse night sky brightness over a wide …