Glioblastoma stem cells are regulated by interleukin-8 signaling in a tumoral perivascular niche
…, BS Lopez, S Mohanan, SC Liu, D Gursel, JA Boockvar… - Cancer research, 2013 - AACR
Glioblastoma multiforme contains a subpopulation of cancer stem–like cells (CSC) believed
to underlie tumorigenesis and therapeutic resistance. Recent studies have localized CSCs …
to underlie tumorigenesis and therapeutic resistance. Recent studies have localized CSCs …
[HTML][HTML] A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the …
RE Kast, JA Boockvar, A Brüning, F Cappello… - Oncotarget, 2013 - ncbi.nlm.nih.gov
To improve prognosis in recurrent glioblastoma we developed a treatment protocol based
on a combination of drugs not traditionally thought of as cytotoxic chemotherapy agents but …
on a combination of drugs not traditionally thought of as cytotoxic chemotherapy agents but …
Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells
…, JM García-Verdugo, NS Roy, JA Boockvar - Journal of neuro …, 2010 - Springer
Recent evidence supports the notion that transformation of undifferentiated neural stem cell (NSC)
precursors may contribute to the development of glioblastoma multiforme (GBM). The …
precursors may contribute to the development of glioblastoma multiforme (GBM). The …
Safety and maximum tolerated dose of superselective intraarterial cerebral infusion of bevacizumab after osmotic blood-brain barrier disruption for recurrent malignant …
JA Boockvar, AJ Tsiouris, CP Hofstetter… - Journal of …, 2011 - thejns.org
… JA Boockvar et al. … JA Boockvar et al. … John Boockvar was supported by the following
grant: National Cancer Institute (NCI) Grant No. CA130985. Dr. …
grant: National Cancer Institute (NCI) Grant No. CA130985. Dr. …
Zero-profile anchored spacer reduces rate of dysphagia compared with ACDF with anterior plating
…, K Kesavabhotla, JA Boockvar - Clinical Spine …, 2015 - journals.lww.com
Study Design: Retrospective cohort study. Objective: To study clinical and radiologic
outcomes after anterior cervical discectomy and fusion (ACDF) using a zero-profile anchored …
outcomes after anterior cervical discectomy and fusion (ACDF) using a zero-profile anchored …
[HTML][HTML] Endoscopic endonasal transsphenoidal surgery for functional pituitary adenomas
…, L Mubita, C Huang, VK Anand, JA Boockvar… - Neurosurgical …, 2011 - thejns.org
Object The purpose of this study was to analyze preoperative predictors of endocrinological
remission following endonasal endoscopic resection of therapy-resistant prolactin-, growth …
remission following endonasal endoscopic resection of therapy-resistant prolactin-, growth …
Intradural spinal tumors in adults—update on management and outcome
…, FH Ruppert, S Schreiber, A Förschler, JA Boockvar… - Neurosurgical …, 2019 - Springer
Among spinal tumors that occur intradurally, meningiomas, nerve sheath tumors, ependymomas,
and astrocytomas are the most common. While a spinal MRI is the state of the art to …
and astrocytomas are the most common. While a spinal MRI is the state of the art to …
Advances in intraoperative optics: a brief review of current exoscope platforms
…, TG White, M Schulder, JA Boockvar… - Operative …, 2020 - journals.lww.com
BACKGROUND The advent of the operating microscope (OM) revolutionized the field of
neurosurgery. It allowed surgeons to operate on and effectively treat diseases previously …
neurosurgery. It allowed surgeons to operate on and effectively treat diseases previously …
Intra-arterial delivery of bevacizumab after blood-brain barrier disruption for the treatment of recurrent glioblastoma: progression-free survival and overall survival
…, CP Hofstetter, AJ Tsiouris, JA Boockvar - World neurosurgery, 2012 - Elsevier
BACKGROUND: This prospective, single-center study assesses progression-free survival (PFS)
and overall survival (OS) in patients with recurrent glioblastoma multiforme (GBM) …
and overall survival (OS) in patients with recurrent glioblastoma multiforme (GBM) …
Results and risk factors for recurrence following single-level tubular lumbar microdiscectomy
…, AR Patel, R Härtl, JA Boockvar - … of Neurosurgery: Spine, 2010 - thejns.org
Object The use of minimally invasive surgical techniques, including microscope-assisted
tubular lumbar microdiscectomy (tLMD), has gained increasing popularity in treating lumbar …
tubular lumbar microdiscectomy (tLMD), has gained increasing popularity in treating lumbar …