User profiles for J.D. Hinman
Jason D HinmanUniversity of California Los Angeles Verified email at mednet.ucla.edu Cited by 3686 |
Post-stroke cognitive impairment and dementia
Poststroke cognitive impairment and dementia (PSCID) is a major source of morbidity and
mortality after stroke worldwide. PSCID occurs as a consequence of ischemic stroke, …
mortality after stroke worldwide. PSCID occurs as a consequence of ischemic stroke, …
Principles of precision medicine in stroke
The era of precision medicine has arrived and conveys tremendous potential, particularly
for stroke neurology. The diagnosis of stroke, its underlying aetiology, theranostic strategies, …
for stroke neurology. The diagnosis of stroke, its underlying aetiology, theranostic strategies, …
[HTML][HTML] Models that matter: white matter stroke models
EG Sozmen, JD Hinman, ST Carmichael - Neurotherapeutics, 2012 - Elsevier
Stroke is a devastating neurological disease with limited functional recovery. Stroke affects
all cellular elements of the brain and impacts areas traditionally classified as both gray matter …
all cellular elements of the brain and impacts areas traditionally classified as both gray matter …
The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS
We have previously shown that myelin abnormalities characterize the normal aging process
of the brain and that an age-associated reduction in Klotho is conserved across species. …
of the brain and that an age-associated reduction in Klotho is conserved across species. …
Remodeling of the axon initial segment after focal cortical and white matter stroke
Background and Purpose— Recovery from stroke requires neuroplasticity within surviving
adjacent cortex. The axon initial segment (AIS) is the site of action potential initiation and a …
adjacent cortex. The axon initial segment (AIS) is the site of action potential initiation and a …
Nogo receptor blockade overcomes remyelination failure after white matter stroke and stimulates functional recovery in aged mice
White matter stroke is a distinct stroke subtype, accounting for up to 25% of stroke and
constituting the second leading cause of dementia. The biology of possible tissue repair after …
constituting the second leading cause of dementia. The biology of possible tissue repair after …
Age‐dependent myelin degeneration and proteolysis of oligodendrocyte proteins is associated with the activation of calpain‐1 in the rhesus monkey
Myelin provides important insulating properties to axons allowing for propagation of action
potentials over large distances at high velocity. Disruption of the myelin sheath could …
potentials over large distances at high velocity. Disruption of the myelin sheath could …
[HTML][HTML] Flow-mediated susceptibility and molecular response of cerebral endothelia to SARS-CoV-2 infection
Background and Purpose: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
infection is associated with an increased rate of cerebrovascular events including ischemic …
infection is associated with an increased rate of cerebrovascular events including ischemic …
MarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocols
The concept of vascular contributions to cognitive impairment and dementia (VCID) derives
from more than two decades of research indicating that (1) most older individuals with …
from more than two decades of research indicating that (1) most older individuals with …
Molecular disorganization of axons adjacent to human lacunar infarcts
Cerebral microvascular disease predominantly affects brain white matter and deep grey
matter, resulting in ischaemic damage that ranges from lacunar infarcts to white matter …
matter, resulting in ischaemic damage that ranges from lacunar infarcts to white matter …