Hydrogen 1 ( 1 H) magnetic resonance (MR) spectroscopy enables noninvasive in vivo
quantification of metabolite concentrations in the brain. Currently, metabolite concentrations are …

Working memory is a temporary storage system under attentional control. It is believed to
play a central role in online processing of complex cognitive information and may also play a …

Neurovascular pathology concurs with protein accumulation, as the brain vasculature is
important for waste clearance. Interstitial solutes, such as amyloid-β, were previously thought to …

Purpose To investigate whether the blood-brain barrier (BBB) leaks blood-circulating substances
in patients with early forms of Alzheimer disease (AD), and if so, to examine the extent …

There is growing interest in the therapeutic utility of psychedelic substances, like psilocybin,
for disorders characterized by distortions of the self-experience, like depression. …

Introduction Psychogenic non-epileptic seizures (PNES) resemble epileptic seizures, but lack
epileptiform brain activity. Instead, the cause is assumed to be psychogenic. An abnormal …

Objective: To study the relation between possibly altered whole brain topology and intellectual
decline in chronic epilepsy, a combined study of neurocognitive assessment and graph …

Magnetic resonance spectroscopy (MRS) is the only biomedical imaging method that can
noninvasively detect endogenous signals from the neurotransmitter γ-aminobutyric acid (GABA…

… Jacobus FA Jansen contributed for analysis support and general support. Matthias JP van
Osch contributed for data acquisition and analysis support. Mark A van Buchem and Majon …

Objective: As blood–brain barrier (BBB) dysfunction may occur in normal aging but may also
play a pivotal role in the pathophysiology of cerebral small vessel disease (cSVD), we used …