[HTML][HTML] Randomized assessment of rapid endovascular treatment of ischemic stroke

…, BK Menon, M Eesa, JL Rempel… - … England Journal of …, 2015 - Mass Medical Soc
Background Among patients with a proximal vessel occlusion in the anterior circulation, 60
to 80% of patients die within 90 days after stroke onset or do not regain functional …

Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial

…, D Haussen, SM Cutting, SB Coutts, D Roy, JL Rempel… - The Lancet, 2020 - thelancet.com
Background Nerinetide, an eicosapeptide that interferes with post-synaptic density protein
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia-reperfusion. …

Analysis of workflow and time to treatment on thrombectomy outcome in the endovascular treatment for small core and proximal occlusion ischemic stroke (ESCAPE) …

BK Menon, TT Sajobi, Y Zhang, JL Rempel, A Shuaib… - Circulation, 2016 - Am Heart Assoc
Background— The Endovascular Treatment for Small Core and Proximal Occlusion Ischemic
Stroke (ESCAPE) trial used innovative imaging and aggressive target time metrics to …

Acute ischemic stroke with tandem lesions: technical endovascular management and clinical outcomes from the ESCAPE trial

…, AM Demchuk, J Shankar, JL Rempel… - Journal of …, 2018 - jnis.bmj.com
Background Tandem occlusions of the extracranial carotid and intracranial carotid or middle
cerebral artery have a particularly poor prognosis without treatment. Several management …

Healthy life-year costs of treatment speed from arrival to endovascular thrombectomy in patients with ischemic stroke: a meta-analysis of individual patient data from 7 …

…, AM Demchuk, BK Menon, M Eesa, JL Rempel… - JAMA …, 2021 - jamanetwork.com
Importance The benefits of endovascular thrombectomy (EVT) are time dependent. Prior
studies may have underestimated the time-benefit association because time of onset is …

Reliability of the diagnosis of cerebral vasospasm using catheter cerebral angiography: a systematic review and inter-and intraobserver study

…, MM Chow, C O'Kelly, JL Rempel… - American Journal …, 2021 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Conventional angiography is the benchmark examination
to diagnose cerebral vasospasm, but there is limited evidence regarding its reliability. Our …

Infarct in a new territory after treatment administration in the ESCAPE randomized controlled trial (endovascular treatment for small core and anterior circulation …

A Ganesh, FS Al-Ajlan, F Sabiq, Z Assis, JL Rempel… - Stroke, 2016 - Am Heart Assoc
Background and Purpose— Infarct in a new previously unaffected territory (INT) is a potential
complication of endovascular treatment. We applied a recently proposed methodology to …

Stent-assisted coiling in the treatment of unruptured intracranial aneurysms: a randomized clinical trial

…, B Drake, H Lesiuk, JL Rempel… - American Journal …, 2023 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Stent-assisted coiling may improve angiographic results
of endovascular treatment of unruptured intracranial aneurysms compared with coiling alone, …

Prognostic evaluation based on cortical vein score difference in stroke

R Parthasarathy, M Kate, JL Rempel, DS Liebeskind… - Stroke, 2013 - Am Heart Assoc
Background and Purpose— Multimodal imaging in acute ischemic stroke defines the extent
of arterial collaterals, resultant penumbra, and associated infarct core, yet limitations abound…

Development and validation of a postprocedural model to predict outcome after endovascular treatment for ischemic stroke

…, TG Jovin, DF Frei, B Sapkota, JL Rempel… - JAMA …, 2023 - jamanetwork.com
Importance Outcome prediction after endovascular treatment (EVT) for ischemic stroke is
important to patients, family members, and physicians. Objective To develop and validate a …