fMRI biomarker of early neuronal dysfunction in presymptomatic Huntington's disease

JS Paulsen, JL Zimbelman, SC Hinton… - American Journal …, 2004 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Functional MR imaging (fMRI) has been used to probe
basal ganglia function in people with presymptomatic Huntington’s disease (pre-HD). A …

Neural modulation of temporal encoding, maintenance, and decision processes

DL Harrington, JL Zimbelman, SC Hinton… - Cerebral …, 2010 - academic.oup.com
Time perception emerges from an interaction among multiple processes that are normally
intertwined. Therefore, a challenge has been to disentangle timekeeping from other processes…

Physical therapy workforce in the United States: forecasting nationwide shortages

JL Zimbelman, SP Juraschek, X Zhang, VWH Lin - PM&R, 2010 - Elsevier
OBJECTIVE: To examine current and future physical therapy (PT) job surplus/shortage trends
across the United States. DESIGN: Forecast models and grading methodology previously …

Neural basis for impaired time reproduction in Parkinson's disease: an fMRI study

CL Elsinger, SM Rao, JL Zimbelman… - Journal of the …, 2003 - cambridge.org
Studies involving brain-lesioned subjects have used the paced finger tapping (PFT) task to
investigate the neural systems that govern motor timing. Patients with Parkinson's disease (…

fMRI detection of early neural dysfunction in preclinical Huntington's disease

JL Zimbelman, JS Paulsen, A Mikos… - Journal of the …, 2007 - cambridge.org
Neuropsychological and neuroimaging changes have been observed in individuals with the
Huntington's disease (HD) gene expansion prior to the onset of manifest HD. This cross-…

Motor timing variability increases in preclinical Huntington's disease patients as estimated onset of motor symptoms approaches

…, NC Reynolds, JL Zimbelman… - Journal of the …, 2007 - cambridge.org
Huntington's disease (HD) is a neurodegenerative disorder diagnosed clinically with the
development of choreiform movements. However, neuropsychological studies have …

Remembering forward: neural correlates of memory and prediction in human motor adaptation

RA Scheidt, JL Zimbelman, NMG Salowitz, AJ Suminski… - Neuroimage, 2012 - Elsevier
We used functional MR imaging (FMRI), a robotic manipulandum and systems identification
techniques to examine neural correlates of predictive compensation for spring-like loads …

Somatotopic organization of the medial wall of the cerebral hemispheres: a 3 Tesla fMRI study

AR Mayer, JL Zimbelman, Y Watanabe, SM Rao - Neuroreport, 2001 - journals.lww.com
Somatotopic organization of the human medial wall of the cerebral hemispheres was studied
using functional MRI conducted at high field strength (3 T) with fine spatial resolution (∼ 2 …

Design and validation of a MR-compatible pneumatic manipulandum

AJ Suminski, JL Zimbelman, RA Scheidt - Journal of neuroscience …, 2007 - Elsevier
The combination of functional MR imaging and novel robotic tools may provide unique
opportunities to probe the neural systems underlying motor control and learning. Here, we …

[BOOK][B] Neural activation patterns of temporal information processing in presymptomatic Huntington's disease

JL Zimbelman - 2004 - search.proquest.com
Timing is essential for skilled movement and perception. Previous fMRI studies in healthy
individuals have observed neural activation of the basal ganglia (BG) during paced finger …