User profiles for John A. Detre

john detre

university of pennsylvania
Verified email at pennmedicine.upenn.edu
Cited by 51103

Perfusion imaging

JA Detre, JS Leigh, DS Williams… - Magnetic resonance in …, 1992 - Wiley Online Library
Measurement of tissue perfusion is important for the functional assessment of organs in vivo.
Here we report the use of 1 H NMR imaging to generate perfusion maps in the rat brain at …

Magnetic resonance imaging of perfusion using spin inversion of arterial water.

DS Williams, JA Detre, JS Leigh… - Proceedings of the …, 1992 - National Acad Sciences
A technique has been developed for proton magnetic resonance imaging (MRI) of perfusion,
using water as a freely diffusable tracer, and its application to the measurement of cerebral …

Comparison of quantitative perfusion imaging using arterial spin labeling at 1.5 and 4.0 Tesla

…, JB Gonzalez‐At, MD Schnall, JA Detre - … in Medicine: An …, 2002 - Wiley Online Library
High‐field arterial spin labeling (ASL) perfusion MRI is appealing because it provides not only
increased signal‐to‐noise ratio (SNR), but also advantages in terms of labeling due to the …

Recommended implementation of arterial spin‐labeled perfusion MRI for clinical applications: a consensus of the ISMRM perfusion study group and the European …

DC Alsop, JA Detre, X Golay, M Günther… - Magnetic resonance …, 2015 - Wiley Online Library
This review provides a summary statement of recommended implementations of arterial
spin labeling (ASL) for clinical applications. It is a consensus of the ISMRM Perfusion Study …

The neural basis of the central executive system of working memory

M D'esposito, JA Detre, DC Alsop, RK Shin, S Atlas… - Nature, 1995 - nature.com
WORKING memory refers to a system for temporary storage and manipulation of information
in the brain, a function critical for a wide range of cognitive operations. It has been proposed …

Reduced transit-time sensitivity in noninvasive magnetic resonance imaging of human cerebral blood flow

DC Alsop, JA Detre - Journal of Cerebral Blood Flow & …, 1996 - journals.sagepub.com
Herein, we present a theoretical framework and experimental methods to more accurately
account for transit effects in quantitative human perfusion imaging using endogenous …

The parahippocampus subserves topographical learning in man

GK Aguirre, JA Detre, DC Alsop, M D'Esposito - Cerebral cortex, 1996 - academic.oup.com
The hippocampus has been proposed as the site of neural representation of large-scale
environmental space, based upon the identification of place cells (neurons with receptive fields …

Magnetic resonance imaging of glutamate

…, F Kogan, JH Greenberg, H Hariharan, JA Detre… - Nature medicine, 2012 - nature.com
Glutamate, a major neurotransmitter in the brain, shows a pH- and concentration-dependent
chemical exchange saturation transfer effect (GluCEST) between its amine group and bulk …

Perfusion functional MRI reveals cerebral blood flow pattern under psychological stress

…, DF Dinges, JA Detre - Proceedings of the …, 2005 - National Acad Sciences
Despite the prevalence of stress in everyday life and its impact on happiness, health, and
cognition, little is known about the neural substrate of the experience of everyday stress in …

Gender difference in neural response to psychological stress

…, J Pluta, RC Gur, BS McEwen, JA Detre - Social cognitive and …, 2007 - academic.oup.com
Gender is an important biological determinant of vulnerability to psychosocial stress. We used
perfusion based functional magnetic resonance imaging (fMRI) to measure cerebral blood …