User profiles for K. Mitsuya

Koichi Mitsuya

Staff, Neurosurgery, Shizuoka Cancer center
Verified email at scchr.jp
Cited by 2042

The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA

…, T Toyoda, K Okamura, S Tajima, K Mitsuya… - Nature, 2007 - nature.com
DNA methyltransferase (cytosine-5) 1 (Dnmt1) is the principal enzyme responsible for
maintenance of CpG methylation and is essential for the regulation of gene expression, silencing …

Role for piRNAs and Noncoding RNA in de Novo DNA Methylation of the Imprinted Mouse Rasgrf1 Locus

T Watanabe, S Tomizawa, K Mitsuya, Y Totoki… - Science, 2011 - science.org
… (A) Methylation status of a portion of the Rasgrf1 DMR [corresponding to a part of region
K in (B)] in spermatogonia from Mili, MitoPLD, and Miwi2 mutants revealed by bisulfite …

Loss of imprinting of a paternally expressed transcript, with antisense orientation to KVLQT1, occurs frequently in Beckwith–Wiedemann syndrome and is …

MP Lee, MR DeBaun, K Mitsuya… - Proceedings of the …, 1999 - National Acad Sciences
… We have previously shown that the K V LQT1 gene on chromosomal … K V LQT1, termed
LIT1 (long QT intronic transcript 1) is expressed normally from the paternal allele, from which K V …

Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation

A Lewis, K Mitsuya, D Umlauf, P Smith, W Dean… - Nature …, 2004 - nature.com
Imprinted genes are expressed from only one of the parental chromosomes and are marked
epigenetically by DNA methylation and histone modifications 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 . The …

Traffic data repository at the {WIDE} project

K Cho, K Mitsuya, A Kato - 2000 USENIX Annual Technical Conference …, 2000 - usenix.org
It becomes increasingly important for both network researchers and operators to know the
trend of network traffic and to find anomaly in their network traffic. This paper describes an on-…

Perfusion weighted magnetic resonance imaging to distinguish the recurrence of metastatic brain tumors from radiation necrosis after stereotactic radiosurgery

K Mitsuya, Y Nakasu, S Horiguchi, H Harada… - Journal of neuro …, 2010 - Springer
After stereotactic radiosurgery (SRS) for brain metastases, delayed radiation effects with
mass effect may occur from several months to years later, when tumors may also recur. …

LIT1, an Imprinted Antisense RNA in the Human KvLQT1 Locus Identified by Screening for Differentially Expressed Transcripts Using Monochromosomal Hybrids

K Mitsuya, M Meguro, MP Lee, M Katoh… - Human Molecular …, 1999 - academic.oup.com
Mammalian imprinted genes are frequently arranged in clusters on particular chromosomes.
The imprinting cluster on human chromosome 11p15 is associated with Beckwith-…

[HTML][HTML] Metastatic skull tumors: MRI features and a new conventional classification

K Mitsuya, Y Nakasu, S Horiguchi, H Harada… - Journal of neuro …, 2011 - Springer
Skull metastases are malignant bone tumors which are increasing in incidence. The
objectives of this study were to characterize the MR imaging features, locations, and extent of …

[HTML][HTML] α-type-1 polarized dendritic cell-based vaccination in recurrent high-grade glioma: a phase I clinical trial

…, K Mitsuya, R Watanabe, T Sugino, K Yamaguchi… - BMC cancer, 2012 - Springer
Background High-grade gliomas including glioblastoma multiforme (GBM) are among the
most malignant and aggressive of tumors, and have a very poor prognosis despite a …

Targeted disruption of the human LIT1 locus defines a putative imprinting control element playing an essential role in Beckwith–Wiedemann syndrome

S Horike, K Mitsuya, M Meguro… - Human molecular …, 2000 - academic.oup.com
Human chromosome 11p15.5 harbors an intriguing imprinted gene cluster of 1 Mb. This
imprinted domain is implicated in a wide variety of malignancies and Beckwith–Wiedemann …