[HTML][HTML] Carotenoids and their isomers: color pigments in fruits and vegetables
Fruits and vegetables are colorful pigment-containing food sources. Owing to their
nutritional benefits and phytochemicals, they are considered as ‘functional food ingredients’. …
nutritional benefits and phytochemicals, they are considered as ‘functional food ingredients’. …
Sarcoma of the breast: an update on a rare entity
SZ Lim, KW Ong, BKT Tan, S Selvarajan… - Journal of clinical …, 2016 - jcp.bmj.com
Breast sarcoma is a rare condition. It consists of a heterogeneous group of non-epithelial
tumours arising from the mesenchymal tissue of the breast. It has a distinctly different natural …
tumours arising from the mesenchymal tissue of the breast. It has a distinctly different natural …
Common variants near MC4R are associated with fat mass, weight and risk of obesity
…, SM Ring, MS Sandhu, A Scherag, MA Sims, K Song… - Nature …, 2008 - nature.com
To identify common variants influencing body mass index (BMI), we analyzed genome-wide
association data from 16,876 individuals of European descent. After previously reported …
association data from 16,876 individuals of European descent. After previously reported …
Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma
Fibroadenomas are the most common breast tumors in women under 30 (refs. 1 , 2 ). Exome
sequencing of eight fibroadenomas with matching whole-blood samples revealed recurrent …
sequencing of eight fibroadenomas with matching whole-blood samples revealed recurrent …
Genomic landscapes of breast fibroepithelial tumors
Breast fibroepithelial tumors comprise a heterogeneous spectrum of pathological entities,
from benign fibroadenomas to malignant phyllodes tumors 1 . Although MED12 mutations …
from benign fibroadenomas to malignant phyllodes tumors 1 . Although MED12 mutations …
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
Here we conducted a large-scale genetic association analysis of educational attainment in
a sample of approximately 1.1 million individuals and identify 1,271 independent genome-…
a sample of approximately 1.1 million individuals and identify 1,271 independent genome-…
Rapid infancy weight gain and subsequent obesity: systematic reviews and hopeful suggestions
In a systematic review, we identified 21 separate studies with data on the association between
rapid infancy weight gain, up to age 2 y, and subsequent obesity risk. Uniformly all studies …
rapid infancy weight gain, up to age 2 y, and subsequent obesity risk. Uniformly all studies …
Genetic variation in LIN28B is associated with the timing of puberty
…, K Northstone, SM Ring, C Rubin, MA Sims, K Song… - Nature …, 2009 - nature.com
The timing of puberty is highly variable 1 . We carried out a genome-wide association study
for age at menarche in 4,714 women and report an association in LIN28B on chromosome 6 (…
for age at menarche in 4,714 women and report an association in LIN28B on chromosome 6 (…
Photodynamic-therapy-activated immune response against distant untreated tumours in recurrent angiosarcoma
PSP Thong, KW Ong, NSG Goh, KW Kho… - The lancet …, 2007 - thelancet.com
We report the case of a 64-year-old Chinese man with histologically proven multifocal
angiosarcoma of the head and neck. To our knowledge, this was the first clinical case in which …
angiosarcoma of the head and neck. To our knowledge, this was the first clinical case in which …
Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer
…, V Tan, B Tan, P Madhukumar, WS Yong, KW Ong… - Science …, 2021 - science.org
Cell state transitions control the functional behavior of cancer cells. Epithelial-to-mesenchymal
transition (EMT) confers cancer stem cell-like properties, enhanced tumorigenicity and …
transition (EMT) confers cancer stem cell-like properties, enhanced tumorigenicity and …