User profiles for Karin M. Muraszko

Karin Muraszko

Verified email at umich.edu
Cited by 15399

[HTML][HTML] Subgroup-specific structural variation across 1,000 medulloblastoma genomes

…, A Jouvet, IF Pollack, X Fan, KM Muraszko… - Nature, 2012 - nature.com
Medulloblastoma, the most common malignant paediatric brain tumour, is currently treated
with nonspecific cytotoxic therapies including surgery, whole-brain radiation, and aggressive …

Near real-time intraoperative brain tumor diagnosis using stimulated Raman histology and deep neural networks

…, TD Johnson, MB Sisti, JN Bruce, KM Muraszko… - Nature medicine, 2020 - nature.com
Intraoperative diagnosis is essential for providing safe and effective care during cancer
surgery 1 . The existing workflow for intraoperative diagnosis based on hematoxylin and eosin …

Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells

…, X He, SL Hervey-Jumper, JA Heth, KM Muraszko… - Cancer research, 2011 - AACR
One important function of endothelial cells in glioblastoma multiforme (GBM) is to create a
niche that helps promote self-renewal of cancer stem-like cells (CSLC). However, the …

Incidence and severity of postoperative cerebellar mutism syndrome in children with medulloblastoma: a prospective study by the Children's Oncology Group

PL Robertson, KM Muraszko, EJ Holmes… - Journal of …, 2006 - thejns.org
Object Cerebellar mutism syndrome (CMS) is a unique postoperative syndrome typically
arising 1 to 2 days after resection of a midline posterior fossa tumor; it consists of diminished …

Prevalence and natural history of arachnoid cysts in children

…, ZE Boomsaad, HJL Garton, KM Muraszko… - Journal of …, 2010 - thejns.org
Object Arachnoid cysts are a frequent finding on intracranial imaging in children. The
prevalence and natural history of these cysts are not well defined. The authors studied a large …

Cytogenetic prognostication within medulloblastoma subgroups

…, JJ Phillips, N Gupta, X Fan, KM Muraszko… - Journal of clinical …, 2014 - ascopubs.org
Purpose Medulloblastoma comprises four distinct molecular subgroups: WNT, SHH, Group 3,
and Group 4. Current medulloblastoma protocols stratify patients based on clinical features…

Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis

…, S Nunes, J Pimentel, X Fan, KM Muraszko… - The lancet …, 2016 - thelancet.com
Background Patients with incomplete surgical resection of medulloblastoma are controversially
regarded as having a marker of high-risk disease, which leads to patients undergoing …

In vivo MR determination of water diffusion coefficients and diffusion anisotropy: correlation with structural alteration in gliomas of the cerebral hemispheres.

…, DA Ross, LR Junck, KM Muraszko… - American Journal …, 1995 - Am Soc Neuroradiology
PURPOSE To determine whether a relationship exists between water diffusion coefficients
or diffusion anisotropy and MR-defined regions of normal or abnormal brain parenchyma in …

Prevalence and natural history of arachnoid cysts in adults

…, S Terman, C Kilburg, HJL Garton, KM Muraszko… - Journal of …, 2013 - thejns.org
Object Arachnoid cysts are a frequent finding on intracranial imaging. The prevalence and
natural history of these cysts in adults are not well defined. Methods We retrospectively …

Evaluation of cancer therapy using diffusion magnetic resonance imaging

…, L Junck, PL Robertson, KM Muraszko… - Molecular cancer …, 2003 - AACR
Assessment of the effectiveness of cancer therapy traditionally relies on comparison of
tumor images acquired before and after therapeutic intervention by inspection of gross …