Evolution of catalytic and regulatory sites in phosphorylases

D Palm, R Goerl, KJ Burger - Nature, 1985 - nature.com
Glycogen phosphorylase (EC2.4.1.1) was the first enzyme shown to be regulated by
allosteric effectors 1 and by protein phosphorylation 2 . Transcriptional control of bacterial …

Local inflammation and devascularization—in vivo mechanisms of the “bystander effect” in VPC-mediated HSV-Tk/GCV gene therapy for human malignant glioma

…, J Felsberg, E Neuen-Jacob, A Aulich, KJ Burger… - Cancer gene …, 2001 - nature.com
Somatic gene therapy with the herpes simplex virus type I thymidine kinase gene/ganciclovir
(HSV-Tk/GCV) system and murine retroviral vector producer cells (VPCs) was introduced …

[HTML][HTML] First-dose analgesic effect of the cyclo-oxygenase-2 selective inhibitor lumiracoxib in osteoarthritis of the knee: a randomized, double-blind, placebo …

…, TOA Fashola, HJ Thurston, KJ Burger… - Arthritis research & …, 2006 - Springer
Cyclo-oxygenase-2 selective inhibitors are frequently used to manage osteoarthritis. We
compared the analgesic efficacy of the novel cyclo-oxygenase-2 selective inhibitor lumiracoxib (…

Purification and characterization of DNA polymerase from the archaebacterium Sulfolobus acidocaldarius

L Klimczak, F Grummt, KJ Burger - Nucleic acids research, 1985 - academic.oup.com
DNA polymerase has been purified about 25,000-fold from the thermoacidophilic
archaebacterium Sulfolobusacidocaldarjus . On SDS-PAGE the enzyme was observed to have a …

MR imaging and single-photon emission CT findings after gene therapy for human glioblastoma

…, A Aulich, KJ Langen, KJ Burger… - American journal …, 2001 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Our goal was to evaluate MR imaging findings after local
intracerebral gene therapy in patients with glioblastoma and differentiate postoperative …

Purification and characterization of DNA polymerase from the archaebacterium Methanobacterium thermoautotrophicum

LJ Klimczak, F Grummt, KJ Burger - Biochemistry, 1986 - ACS Publications
DNA polymerase from the thermophilic archaebacterium Methanobacterium thermoautotrophicum
was purified about 16000-fold by chromatography on heparin-agarose, Blue …

A site-specific endonuclease activity in Halobacterium halobium

R Schinzel, KJ Burger - FEMS microbiology letters, 1986 - academic.oup.com
In Halobacterium halobium and some related strains, a site-specific endonuclease activity
was found. This activity requires 3 M NaCl and 5–10 mM Mg 2+ ions for function. The 3 …

Expression of antibiotic resistance genes from Escherichia coli in Bacillus subtilis

J Kreft, KJ Burger, W Goebel - Molecular and General Genetics MGG, 1983 - Springer
Bifunctional recombinant plasmids were constructed, comprised of the E. coli vectors pBR322,
pBR325 and pACYC184 and different plasmids from Gram-positive bacteria, eg pBSU161…

Calcium antagonists as first-line antihypertensive agents: a placebo-controlled, comparative trial of isradipine and nifedipine

D Wetzel, KJ Burger, G Weidinger - Journal of cardiovascular …, 1990 - journals.lww.com
The new calcium antagonist isradipine was compared with nifedipine retard in a multicenter,
double-blind, placebo-controlled, randomized study involving 159 patients with mild …

Expression and instability of heterologous genes in B. subtilis

J Kreft, J Parrisius, KJ Burger… - Molecular cloning and …, 1982 - books.google.com
Several years ago we isolated and partially characterized a large number of plasmids which
were obtained from natural Bacillus isolates, mainly from the species Bacillus cereus (…