Progressive derangement of periinfarct viable tissue in ischemic stroke

…, U Pietrzyk, R Wagner, K Wienhard - Journal of Cerebral …, 1992 - journals.sagepub.com
Sixteen patients were studied by multitracer positron emission tomography (PET) within 6–48
(mean of 23) h of onset of a hemispheric ischemic stroke and again 13–25 (mean of 15.6) …

The ECAT EXACT HR: performance of a new high resolution positron scanner

K Wienhard, M Dahlbom, L Eriksson… - Journal of computer …, 1994 - journals.lww.com
Objective The ECAT EXACT HR is a newly designed CTI–Siemens PET scanner with high
spatial resolution. Its physical performance with respect to resolution, count rate efficiency, …

The ECAT HRRT: performance and first clinical application of the new high resolution research tomograph

K Wienhard, M Schmand, ME Casey… - … on Nuclear Science, 2002 - ieeexplore.ieee.org
The ECAT HRRT is a three-dimensional (3-D) only dedicated brain tomograph employing
the new scintillator lutetium-oxy-orthosilicate (LSO) and using depth of interaction (DOI) …

18F-fluoro-L-thymidine and 11C-methylmethionine as markers of increased transport and proliferation in brain tumors

…, S Vollmar, K Herholz, K Wienhard… - Journal of Nuclear …, 2005 - Soc Nuclear Med
Because of the high glucose metabolism in normal brain tissue 18 F-FDG is not the ideal
tracer for the detection of gliomas. Methyl- 11 C-l-methionine ( 11 C-MET) is better suited for …

Performance evaluation of the microPET R4 PET scanner for rodents

…, A Jacobs, RN Goble, R Graf, K Wienhard… - European journal of …, 2003 - Springer
The microPET R4 scanner is a dedicated positron emission tomograph (PET) for studies of
rodents. A number of scanner parameters such as spatial resolution, sensitivity, scatter, and …

Direct demonstration of transcallosal disinhibition in language networks

A Thiel, B Schumacher, K Wienhard… - Journal of Cerebral …, 2006 - journals.sagepub.com
Neuroimaging studies in right-handed patients with left hemisphere brain lesions have
demonstrated a shift of language activity from left to right inferior frontal gyrus (IFG). This shift may …

Deep brain stimulation of the subthalamic nucleus does not increase the striatal dopamine concentration in parkinsonian humans

…, A Koulousakis, K Herholz, K Wienhard… - … : official journal of the …, 2003 - Wiley Online Library
Deep brain stimulation of the subthalamic nucleus (STN‐DBS) has become an effective
treatment option in advanced Parkinson's disease (PD). Recent animal studies showed an …

Early [11C]Flumazenil/H2O Positron Emission Tomography Predicts Irreversible Ischemic Cortical Damage in Stroke Patients Receiving Acute Thrombolytic Therapy

…, L Kracht, M Grond, J Rudolf, B Bauer, K Wienhard… - Stroke, 2000 - Am Heart Assoc
Background and Purpose—Central benzodiazepine receptor ligands, such as [ 11 C]flumazenil
(FMZ), are markers of neuronal integrity and therefore might be useful in the …

Glioma Proliferation as Assessed by 3'-Fluoro-3'-Deoxy-l-Thymidine Positron Emission Tomography in Patients with Newly Diagnosed High-Grade Glioma

…, K Kesper, B Neumaier, WD Heiss, K Wienhard… - Clinical cancer …, 2008 - AACR
Purpose: The aim of this study was to investigate the relationship between the in vivo derived
kinetic parameters of 3′-deoxy-3′- 18 F-fluorothymidine ( 18 F-FLT) and the proliferation …

Individual functional anatomy of verb generation

K Herholz, A Thiel, K Wienhard, U Pietrzyk… - Neuroimage, 1996 - Elsevier
Examination of the individual functional anatomy of language is of particular interest in clinical
neurology to explain the variability of aphasic symptoms after focal lesions and to avoid …