INTRODUCTION Brain disorders may exhibit shared symptoms and substantial epidemiological
comorbidity, inciting debate about their etiologic overlap. However, detailed study of …

We are researchers and clinicians working on Alzheimer’s disease (AD) or related topics,
and we write to express our concern that one particular aspect of the disease has been …

Eleven susceptibility loci for late-onset Alzheimer's disease (LOAD) were identified by previous
studies; however, a large portion of the genetic risk for this disease remains unexplained. …

… On the nervous system, behavioral changes after alcohol intake vary according to the
quantity of ethanol ingested: psycho-stimulation if the quantity is lower than 0.5 g/l, and sedation …

Objective: To investigate the risk of AD associated with a family history of dementia, female
gender, low levels of education, smoking, and head trauma. Background: These putative …

The gene encoding apolipoprotein E (APOE) on chromosome 19 is the only confirmed
susceptibility locus for late-onset Alzheimer's disease. To identify other risk loci, we conducted a …

Objective: To estimate the age-specific incidence rate of mild cognitive impairment (MCI)
according to sex and educational level and to explore the course of MCI, particularly its …

Objective: To study the difference in risk for dementing diseases between men and women.
Background: Previous studies suggest women have a higher risk for dementia than men. …

Background: Dietary fatty acids and antioxidants may contribute to decrease dementia risk,
but epidemiologic data remain controversial. The aim of our study was to analyze the …

Alcoholism is a possible cause of dementia, mainly through associated nutritional deficiencies
and, rarely, through acute direct toxicity. However alcohol consumption was not found to …