Background Carbamazepine, an anticonvulsant and a mood-stabilizing drug, is the main
cause of the Stevens–Johnson syndrome (SJS) and its related disease, toxic epidermal …

Neuropathic pain indicates pain caused by damage to the somatosensory system and is
difficult to manage and treat. A new treatment strategy urgently needs to be developed. Both …

Background Family genetic testing of patients newly diagnosed with a rare genetic disease
can improve early diagnosis of family members, allowing patients to receive disease‐specific …

BACKGROUND: Myelitis is a rare complication of varicella zoster virus (VZV) infection and
is more prevalent in immunocompromised individuals. Clinical features, outcomes, and …

Objective The glymphatic system cleans amyloid and tau proteins from the brain in animal
studies of Alzheimer disease (AD). However, there is no direct evidence showing this in …

The systemic administration of anti-nerve growth factor (NGF) antibodies can prevent local
sensory hypersensitivity and block nociceptive fibers from sprouting into denervated adult rat …

We report the MR findings in two cases of Hirayama disease, a kind of cervical myelopathy
related to flexion movements of the neck. In flexion MR studies, we can see the striking and …

Background During inflammation, immune cells accumulate in damaged areas and release
pro-inflammatory cytokines and neurotrophins. Brain-derived neurotrophic factor (BDNF) …

Importance Transthyretin gene silencing is an emerging treatment strategy for hereditary
transthyretin (ATTRv) amyloidosis. Objective To evaluate eplontersen, an investigational ligand-…

The purpose of this study was to review the clinical manifestations of 40 patients who
fulfilled the clinical criteria for Hirayama disease (juvenile muscular atrophy of distal upper …