Intracranial aneurysms (IAs) linger as a potentially devastating clinical problem. Despite
intense investigation, our understanding of the mechanisms leading to aneurysm development, …

Background and Purpose— Self-expanding stents are increasingly used for treatment of
complex intracranial aneurysms. We assess the safety and the efficacy of intracranial stenting …

Background and Purpose— Flow diversion has emerged as an important tool for the
management of intracranial aneurysms. The purpose of this study was to compare flow diversion …

OBJECTIVE: This study was designed to quantify the operative exposure obtained in the
pterional, orbitozygomatic, and modified orbitozygomatic with maxillary extension surgical …

Little is known about vascular smooth muscle cell (SMC) phenotypic modulation in the
cerebral circulation or pathogenesis of intracranial aneurysms. Tumor necrosis factor-alpha (TNF-…

Smoking is an established risk factor for subarachnoid hemorrhage yet the underlying
mechanisms are largely unknown. Recent data has implicated a role of inflammation in the …

Oxidative stress is known to contribute to the progression of cerebrovascular disease.
Additionally, oxidative stress may be increased by, but also augment inflammation, a key …

✓ The goal of this study was to develop a new method for neurosurgical education based on
interactive stereoscopic virtual reality (ISVR). Interactive stereoscopic virtual reality can be …

BACKGROUND: The Pipeline Embolization Device (PED) has emerged as a promising
treatment for intracranial aneurysms. OBJECTIVE: To assess the safety and efficacy of the PED, …

BACKGROUND: Endovascular therapy is now the preferred treatment option for basilar tip
aneurysms (BTAs). OBJECTIVE: To compare the safety and efficacy of common endovascular …