User profiles for L. Osaki

Luciana Harumi Osaki

Verified email at usp.br
Cited by 566

[HTML][HTML] MAPKs and signal transduction in the control of gastrointestinal epithelial cell proliferation and differentiation

LH Osaki, P Gama - International journal of molecular sciences, 2013 - mdpi.com
Mitogen-activated protein kinase (MAPK) pathways are activated by several stimuli and
transduce the signal inside cells, generating diverse responses including cell proliferation, …

[HTML][HTML] Gastric organoids: progress and remaining challenges

…, JR Burclaff, R Jin, M Adkins-Threats, LH Osaki… - Cellular and Molecular …, 2022 - Elsevier
The stomach is a complex and physiologically necessary organ, yet large differences in
physiology between mouse and human stomachs have impeded translation of physiological …

Interferon‐γ directly induces gastric epithelial cell death and is required for progression to metaplasia

LH Osaki, KA Bockerstett, CF Wong… - The Journal of …, 2019 - Wiley Online Library
Chronic inflammation of the gastric mucosa, often caused by autoimmune gastritis and/or
infection with Helicobacter pylori, can lead to atrophy of acid‐secreting parietal cells with …

[PDF][PDF] A metformin-responsive metabolic pathway controls distinct steps in gastric progenitor fate decisions and maturation

ZF Miao, M Adkins-Threats, JR Burclaff, LH Osaki… - Cell Stem Cell, 2020 - cell.com
Cellular metabolism plays important functions in dictating stem cell behaviors, although its
role in stomach epithelial homeostasis has not been evaluated in depth. Here, we show that …

Targeted apoptosis of parietal cells is insufficient to induce metaplasia in stomach

J Burclaff, LH Osaki, D Liu, JR Goldenring, JC Mills - Gastroenterology, 2017 - Elsevier
Osaki and Dengqun Liu were responsible for data collection and analysis; James R.
Goldenring performed data interpretation, supplied a reagent, and edited the manuscript; and …

Magnetic resonance imaging in patients with congenital heart disease.

CB Higgins, BF Byrd 3rd, DW Farmer, L Osaki… - Circulation, 1984 - Am Heart Assoc
… abnormalities of the great vessels, including anterior and rightward position of the aorta
in a patient with D-transposition, anterior and leftward position of the aorta in a patient with L-…

[HTML][HTML] Interleukin-17A promotes parietal cell atrophy by inducing apoptosis

KA Bockerstett, LH Osaki, CP Petersen, CW Cai… - Cellular and Molecular …, 2018 - Elsevier
Background & Aims Atrophic gastritis caused by chronic inflammation in the gastric mucosa
leads to the loss of gastric glandular cells, including acid-secreting parietal cells. Parietal cell …

Congenital heart disease: gated MR imaging in 72 patients.

D Didier, CB Higgins, MR Fisher, L Osaki… - Radiology, 1986 - pubs.rsna.org
… Fisher, MD #{149}Luci Osaki, … and an Lventricular … vessels and left superior vena
cava (L SVC). (b) Aorta is also left-sided and arises from the rudimentary …

Magnetic resonance imaging in pulmonary arterial hypertension

…, CB Higgins, BF Byrd, EG Amparo, L Osaki… - The American journal of …, 1985 - Elsevier
… The presence of signal in the PAS was graded from 1 to 5 by the following criteria: l/5 for
PA signal present only on the image at end diastole and 215 for signal present on 2 images, …

Gd-DTPA in clinical MR of the brain: 1. Intraaxial lesions

M Brant-Zawadzki, I Berry, L Osaki… - American journal …, 1986 - Am Soc Neuroradiology
Over 35 intraaxial lesions in 15 patients suspected of having intracranial tumors were studied
with MR before and after injection of Gadolinium-DTPA (Gd-DTPA). Diseases included …