Multiple sclerosis lesion quantification using fuzzy-connectedness principles

JK Udupa, L Wei, S Samarasekera… - … on medical imaging, 1997 - ieeexplore.ieee.org
Multiple sclerosis (MS) is a disease of the white matter. Magnetic resonance imaging (MRI)
is proven to be a sensitive method of monitoring the progression of this disease and of its …

Brain atrophy in relapsing-remitting multiple sclerosis and secondary progressive multiple sclerosis: longitudinal quantitative analysis

Y Ge, RI Grossman, JK Udupa, L Wei, LJ Mannon… - Radiology, 2000 - pubs.rsna.org
PURPOSE: To determine annual rates of volumetric changes in the whole-brain parenchyma
of patients with relapsing-remitting and secondary progressive multiple sclerosis (MS) and …

Comparison of T2 lesion volume and magnetization transfer ratio histogram analysis and of atrophy and measures of lesion burden in patients with multiple sclerosis.

…, RI Grossman, Y Miki, L Wei… - American Journal …, 1998 - Am Soc Neuroradiology
PURPOSE The purpose of this study was twofold: first, to compare two different measures of
lesion burden in patients with multiple sclerosis (MS), the magnetization transfer ratio (MTR) …

Efficient method for multiscale small target detection from a natural scene

G Wang, T Zhang, L Wei, N Sang - Optical Engineering, 1996 - spiedigitallibrary.org
According to the principle of human discrimination of small targets from a natural scene that
there is a signature of discontinuity between the object and its neighboring regions, we …

MR lesion load and cognitive function in patients with relapsing-remitting multiple sclerosis

…, LJ Mannon, M Grossman, L Wei… - American journal …, 1999 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Multiple sclerosis (MS) is a demyelinating disease most
often associated with progressive physical impairment; however, its effects are noted to extend …

Relapsing-remitting multiple sclerosis: longitudinal analysis of MR images—lack of correlation between changes in T2 lesion volume and clinical findings

Y Miki, RI Grossman, JK Udupa, L Wei, M Polansky… - Radiology, 1999 - pubs.rsna.org
PURPOSE: To determine the relationship between T2 lesion volume and either disability
measurements or change in T2 lesion volume over time in multiple sclerosis (MS). MATERIALS …

MR imaging quantitation of gray matter involvement in multiple sclerosis and its correlation with disability measures and neurocognitive testing

…, D Kolson, M Grossman, L Wei… - American journal …, 1999 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Multiple sclerosis (MS) is the most common inflammatory
disease of the central nervous system and manifests both physical and neurocognitive …

Numerical tissue characterization in MS via standardization of the MR image intensity scale

Y Ge, JK Udupa, LG Nyul, L Wei… - Journal of Magnetic …, 2000 - Wiley Online Library
Image intensity standardization is a recently developed postprocessing method that is capable
of correcting the signal intensity variations in MR images. We evaluated signal intensity of …

Multiple sclerosis: magnetization transfer histogram analysis of segmented normal-appearing white matter

…, RI Grossman, DL Kolson, JK Udupa, LG Nyul, L Wei… - Radiology, 2000 - pubs.rsna.org
PURPOSE: To investigate and characterize the global distribution of magnetization transfer (MT)
ratio values of normal-appearing white matter (NAWM) in patients with relapsing-…

Differences between relapsing-remitting and chronic progressive multiple sclerosis as determined with quantitative MR imaging

…, RI Grossman, JK Udupa, MA van Buchem, L Wei… - Radiology, 1999 - pubs.rsna.org
PURPOSE: To investigate the cross-sectional relationships among multiple quantitative
brain magnetic resonance (MR) imaging measurements in patients with relapsing-remitting …