8;21 translocation was found in 10 AML patients. These patients exhibited a distinct clinical
and haematological picture, characterized by M2 bone marrow, with rather good maturation, …

A previously healthy boy was admitted to hospital 5 times from age 18 months to 2 to 5 years
with recurring ketotic acidosis. Abnormalities observed during attacks comprised an anion …

Orbital fat edema was found in a patient with long-standing severe anorexia nervosa. The
changes disappeared after the patient gained weight. The underlying mechanisms remains …

There is convincing evidence that inflammation plays a pivotal role in the pathophysiology
of complex regional pain syndrome ( CRPS ). Besides inflammation, central sensitization is …

A 7‐year‐old boy developed renal tubular dysfunction and hypophosphatemic rickets
following treatment for relapsed embryonal rhabdomyosarcoma. Multi‐agent chemotherapy …

A bone marrow transplantation was performed in 30 patients because of leukaemia or severe
aplastic anaemia. The donor was a monozygous twin in 2 cases, a HLA-matched sibling in …

A young child with neurofibromatosis type 1 (NF1) is reported who developed two primary
malignancies: a glioblastoma, followed 6 months later by an abdominal B cell non‐Hodgkin's …

… MC-mediators rather than from actual tissue invasion by MC. Clinical experience with KIT-targeting
TKI in indolent systemic mastocytosis is limited. The multi-TKI masitinib was found to …

A 14-year-old boy with a two year history of seronegative rheumatoid arthritis developed left
leg lymphedema and subsequently a severe episode of lymphangitis. The diagnosis of" …

… (Erasmus MC) … MC cohort no significant differences in morbidity appeared between the
ethnic groups. However, uveitis and pustules were significantly more common in the Erasmus MC …