Reciprocal signalling between immunocompetent cells in the central nervous system (CNS)
has emerged as a key phenomenon underpinning pathological and chronic pain …

… The programmes developed by Hutchinson have been widely used to develop climate
interpolation relationships for other parts of the world. See, for example, papers describing the …

Workplace bullying is a significant issue confronting the nursing profession. Bullying in nursing
is frequently described in terms of ‘oppressed group’ behaviour or ‘horizontal violence’. It …

New evidence and consensus has led to further revision of the McDonald Criteria for diagnosis
of multiple sclerosis. The use of imaging for demonstration of dissemination of central …

Background Natalizumab is the first α 4 integrin antagonist in a new class of selective
adhesion-molecule inhibitors. We report the results of a two-year phase 3 trial of natalizumab in …

Background and Methods Multiple sclerosis often occurs in young women, and the effect of
pregnancy on the disease is poorly understood. We studied 254 women with multiple …

Background BG-12 (dimethyl fumarate) is in development as an oral treatment for relapsing–remitting
multiple sclerosis, which is commonly treated with parenteral agents (interferon or …

A morphological approach to the interpolation of regular grid digital elevation models (DEMs)
from surface specific elevation data points and selected stream lines is described. The …

Effective and targeted conservation action requires detailed information about species, their
distribution, systematics and ecology as well as the distribution of threat processes which …

Background and objectives Diagnosis of multiple sclerosis (MS) requires exclusion of diseases
that could better explain the clinical and paraclinical findings. A systematic process for …