Ways toward an early diagnosis in Alzheimer's disease: the Alzheimer's Disease Neuroimaging Initiative (ADNI)

SG Mueller, MW Weiner, LJ Thal, RC Petersen… - Alzheimer's & …, 2005 - Elsevier
With the increasing life expectancy in developed countries, the incidence of Alzheimer’s
disease (AD) and thus its socioeconomic impact are growing. Increasing knowledge over the …

The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception

MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2013 - Elsevier
… Michael Weiner and Leon Thal (since deceased) proposed a longitudinal MRI study of
AD, MCI, and control subjects. Subsequently, Dr. Buckholz brought together a number of …

Cognition and anatomy in three variants of primary progressive aphasia

…, HJ Rosen, JK Johnson, MW Weiner… - Annals of Neurology …, 2004 - Wiley Online Library
We performed a comprehensive cognitive, neuroimaging, and genetic study of 31 patients
with primary progressive aphasia (PPA), a decline in language functions that remains isolated …

Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease

…, B Reed, D Norman, HC Chui, MW Weiner - Journal of Neurology …, 2001 - jnnp.bmj.com
OBJECTIVES To explore volume changes of the entorhinal cortex (ERC) and hippocampus
in mild cognitive impairment (MCI) and Alzheimer's disease (AD) compared with normal …

The Alzheimer's disease neuroimaging initiative

SG Mueller, MW Weiner, LJ Thal… - Neuroimaging …, 2005 - neuroimaging.theclinics.com
With increasing life expectancy in developed countries, diseases typically associated with old
age are becoming more frequent and, thus, increasingly gain in socioeconomic importance…

The Alzheimer's disease neuroimaging initiative (ADNI): MRI methods

…, G Glover, J Mugler, MW Weiner - Journal of Magnetic …, 2008 - Wiley Online Library
The Alzheimer's Disease Neuroimaging Initiative (ADNI) is a longitudinal multisite observational
study of healthy elders, mild cognitive impairment (MCI), and Alzheimer's disease. …

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

…, WJ Jagust, LM Shaw, PS Aisen, MW Weiner… - The Lancet …, 2010 - thelancet.com
Currently available evidence strongly supports the position that the initiating event in
Alzheimer's disease (AD) is related to abnormal processing of β-amyloid (Aβ) peptide, ultimately …

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

…, WJ Jagust, RC Petersen, MW Weiner… - The lancet …, 2013 - thelancet.com
In 2010, we put forward a hypothetical model of the major biomarkers of Alzheimer's disease
(AD). The model was received with interest because we described the temporal evolution of …

Alzheimer's disease Neuroimaging Initiative (ADNI) clinical characterization

…, LM Shaw, AW Toga, JQ Trojanowski, MW Weiner - Neurology, 2010 - AAN Enterprises
Weiner serves on scientific advisory boards for Bayer Schering Pharma, Eli Lilly and
Company, CoMentis, Inc., Neurochem Inc, Eisai Inc., Avid Radiopharmaceuticals Inc., Aegis …

Episodic memory loss is related to hippocampal-mediated β-amyloid deposition in elderly subjects

…, BL Miller, RA Koeppe, CA Mathis, MW Weiner… - Brain, 2009 - academic.oup.com
Although β-amyloid (Aβ) plaques are a primary diagnostic criterion for Alzheimer's disease,
this pathology is commonly observed in the brains of non-demented older individuals. To …