Neuroprotection for ischemic stroke refers to strategies, applied singly or in combination, that
antagonize the injurious biochemical and molecular events that eventuate in irreversible …

… Ann Neurol 1985;18:329-336 Harik SI, Yoshida S, Busto R, Ginsberg MD: Monoamine …
Neurology 1986:36:971-976 Busto R, Ginsberg MD: Graded focal cerebral ischemia in the …

Background—Moderate elevations of brain temperature, when present during or after
ischemia or trauma, may markedly worsen the resulting injury. We review these provocative …

We have tested whether small intraischemic variations in brain temperature influence the
outcome of transient ischemia. To measure brain temperature, a thermocouple probe was …

… Dietrich WD, Busto R, Ginsberg MD: Cerebral endothelial microvilli: formation following
global forebrain ischemia. J Neuropathol Neurol 43:72-83, 1984 11. Dietrich WD, Watson BD, …

… Busto R, Harik SI, Yoshida S, Scheinberg P, Ginsberg MD: Cerebral norepinephrine …
Yoshida S, Harik SI, Busto R, Santiso M, Martinez E, Ginsberg MD: Free fatty acids and energy …

Background and Purpose The purpose of the present study was to evaluate a modified
method of intraluminal suture occlusion of the middle cerebral artery (MCA) on the volume of …

Posttraumatic hypothermia reduces the extent of neuronal damage in remote cortical and
subcortical structures following traumatic brain injury (TBI). We evaluated whether excessive …

A sensitive quantitative fluorescence method was used to explore the time course and
regional pattern of blood-brain barrier (BBB) opening after transient middle cerebral artery …

We have previously described a marked attenuation of postischemic striatal neuronal death
by prior substantia nigra (SN) lesioning. The present study was carried out to evaluate …