User profiles for M. L. Wynn
Michelle L WynnGoogle X Verified email at umich.edu Cited by 481 |
Logic-based models in systems biology: a predictive and parameter-free network analysis method
Highly complex molecular networks, which play fundamental roles in almost all cellular
processes, are known to be dysregulated in a number of diseases, most notably in cancer. As a …
processes, are known to be dysregulated in a number of diseases, most notably in cancer. As a …
The importance of accurately correcting for the natural abundance of stable isotopes
The use of isotopically labeled tracer substrates is an experimental approach for measuring
in vivo and in vitro intracellular metabolic dynamics. Stable isotopes that alter the mass but …
in vivo and in vitro intracellular metabolic dynamics. Stable isotopes that alter the mass but …
Safety and efficacy of delayed intraarterial urokinase therapy with mechanical clot disruption for thromboembolic stroke.
…, TT Nguyen, OR O'Neill, ML Wynn… - American Journal …, 1994 - Am Soc Neuroradiology
… therapy, usually with 500 mL of a colloid solution, and … was then infused in 1-mL volumes
(50 000 U/mL) as a bolus into the … a gentle pulse spray of 0.10 mL, delivering 1 mL over 5 to 10 …
(50 000 U/mL) as a bolus into the … a gentle pulse spray of 0.10 mL, delivering 1 mL over 5 to 10 …
Running faster causes disaster: trade-offs between speed, manoeuvrability and motor control when running around corners in northern quolls (Dasyurus hallucatus)
ML Wynn, C Clemente, AFAA Nasir… - Journal of …, 2015 - journals.biologists.com
Movement speed is fundamental to all animal behaviour, yet no general framework exists
for understanding why animals move at the speeds they do. Even during fitness-defining …
for understanding why animals move at the speeds they do. Even during fitness-defining …
Safety and efficacy of percutaneous transluminal angioplasty for intracranial atherosclerotic stenosis
WM Clark, SL Barnwell, G Nesbit, OR O'neill, ML Wynn… - Stroke, 1995 - Am Heart Assoc
Background and Purpose Percutaneous transluminal angioplasty (PCTA) is increasingly used
to treat extracerebral arterial stenosis. The present study evaluates the safety and efficacy …
to treat extracerebral arterial stenosis. The present study evaluates the safety and efficacy …
[HTML][HTML] Adipocytes promote pancreatic cancer cell proliferation via glutamine transfer
… μg/ml insulin, 0.25 μM dexamethasone, 2 μM rosiglitazone for 3 days, followed by culture in
DMEM, 10%FCS, 1 μg/ml insulin … Final media volume was raised to 1 ml per manufacturer's …
DMEM, 10%FCS, 1 μg/ml insulin … Final media volume was raised to 1 ml per manufacturer's …
[HTML][HTML] Kinase inhibitors can produce off-target effects and activate linked pathways by retroactivity
Background It has been shown in experimental and theoretical work that covalently modified
signaling cascades naturally exhibit bidirectional signal propagation via a phenomenon …
signaling cascades naturally exhibit bidirectional signal propagation via a phenomenon …
Follow-the-leader cell migration requires biased cell–cell contact and local microenvironmental signals
… The ABM used in this work was an extension of a simulation framework previously developed
(Wynn et al 2012). While the ABM presented here differs from the two ABMs previously …
(Wynn et al 2012). While the ABM presented here differs from the two ABMs previously …
Sex-specific trade-offs and compensatory mechanisms: bite force and sprint speed pose conflicting demands on the design of geckos (Hemidactylus frenatus)
SF Cameron, ML Wynn… - Journal of Experimental …, 2013 - journals.biologists.com
One of the more intuitive viability costs that can result from the possession of exaggerated
sexually selected traits is increased predation pressure as a result of reduced locomotor …
sexually selected traits is increased predation pressure as a result of reduced locomotor …
[HTML][HTML] RhoC GTPase is a potent regulator of glutamine metabolism and N-acetylaspartate production in inflammatory breast cancer cells
… /ml insulin, 0.5 μg/ml hydrocortisone, 0.02 μg/ml epidermal growth factor, and 0.1 μg/ml cholera
… with 5% FBS, 5 μg/ml insulin, and 1 μg/ml hydrocortisone. Cells were grown in 5% CO 2 …
… with 5% FBS, 5 μg/ml insulin, and 1 μg/ml hydrocortisone. Cells were grown in 5% CO 2 …