Ultrasound in the treatment of ischaemic stroke

M Daffertshofer, M Hennerici - The Lancet Neurology, 2003 - thelancet.com
Intravenous alteplase (recombinant tissue plasminogen activator) has been shown to be
beneficial within a short 3 h window after stroke. Ultrasound has a thrombolytic capacity that …

Transcranial low-frequency ultrasound-mediated thrombolysis in brain ischemia: increased risk of hemorrhage with combined ultrasound and tissue plasminogen …

M Daffertshofer, A Gass, P Ringleb, M Sitzer, U Sliwka… - Stroke, 2005 - Am Heart Assoc
Background— Clinical studies using ultrasound at diagnostic frequencies in transcranial
Doppler devices provided encouraging results in enhancing thrombolysis with tissue …

Proinflammatory cytokines in serum of patients with acute cerebral ischemia: kinetics of secretion and relation to the extent of brain damage and outcome of disease

…, T Kammer, M Daffertshofer, S Wirth, M Dollman… - Journal of the …, 1994 - Elsevier
The release of the proinflammatory cytokines IL-1β, IL-6, TNF-α and soluble TNF-receptors
p55 and p75 in peripheral blood was serially determined in 19 patients with acute cerebral …

High-intensity transient signals in patients with cerebral ischemia

M Daffertshofer, S Ries, U Schminke, M Hennerici - Stroke, 1996 - Am Heart Assoc
Background and Purpose This study investigated the diagnostic relevance of transcranial
Doppler monitoring for the detection of high-intensity transient signals (HITS) in patients with …

COVID‐19 vaccine‐associated cerebral venous thrombosis in Germany

…, M Daffertshofer, M Dafotakis, M Dieterich… - Annals of …, 2021 - Wiley Online Library
Objective We aimed to estimate the incidence of cerebral sinus and venous thrombosis (CVT)
within 1 month from first dose administration and the frequency of vaccine‐induced …

Cohort study of multiple brain lesions in sport divers: role of a patent foramen ovale

…, T Kerby, M Forsting, M Daffertshofer, M Hennerici… - Bmj, 1997 - bmj.com
… Michael Daffertshofer, neurologistb, … We are indebted to Dr HP Altenburg for his advice
on statistical methodology and to M Garcia for her editorial … Articles by Michael Daffertshofer

Pattern of activation of the hypothalamic-pituitary-adrenal axis in acute stroke. Relation to acute confusional state, extent of brain damage, and clinical outcome.

…, R Schmidt, R Mössner, M Daffertshofer, M Hennerici - Stroke, 1994 - Am Heart Assoc
The aim of this study was to characterize the response of the hypothalamic-pituitary-adrenal
system in the first hours of ischemic stroke and to relate its extent to the occurrence of acute …

Leakage of brain-originated proteins in peripheral blood: temporal profile and diagnostic value in early ischemic stroke

…, M Fatar, F Mühlhauser, M Daffertshofer… - Journal of the …, 1997 - Elsevier
The clinical value of determination of CNS-specific proteins in peripheral blood at the acute
phase of ischemic stroke is unclear. S-100 protein and neurone specific enolase were …

Stroke recurrences in patients with symptomatic vs asymptomatic middle cerebral artery disease

…, W Steinke, M Daffertshofer, R Prager, M Hennerici - Neurology, 2005 - AAN Enterprises
Background: Although the natural history of extracranial carotid artery disease has been
investigated systematically, limited data are available on the course of middle cerebral artery (…

Therapeutic ultrasound in ischemic stroke treatment: experimental evidence

M Daffertshofer, M Fatar - European journal of ultrasound, 2002 - Elsevier
Re-opening of the occluded artery is the primary therapeutic goal in hyper-acute ischemic
stroke. Systemic treatment with IV rt-PA has been shown to be beneficial at least in a 3 h ‘door …