User profiles for M. Hoshi
Masato HoshiWashington University School of Medicine Verified email at wustl.edu Cited by 2006 |
[HTML][HTML] Amyloid β-protein assembly and Alzheimer disease
R Roychaudhuri, M Yang, MM Hoshi… - Journal of Biological …, 2009 - ASBMB
The biochemistry of amyloid proteins has been a fascinating and important area of research
because of its contribution to our understanding of protein folding dynamics and assembly …
because of its contribution to our understanding of protein folding dynamics and assembly …
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
Using the ImmunoChip custom genotyping array, we analyzed 14,498 subjects with multiple
sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 …
sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 …
An automated tool for detection of FLAIR-hyperintense white-matter lesions in multiple sclerosis
…, M Arsic, D Buck, A Förschler, A Berthele, M Hoshi… - Neuroimage, 2012 - Elsevier
In Multiple Sclerosis (MS), detection of T2-hyperintense white matter (WM) lesions on
magnetic resonance imaging (MRI) has become a crucial criterion for diagnosis and predicting …
magnetic resonance imaging (MRI) has become a crucial criterion for diagnosis and predicting …
Risk of Thyroid Cancer After Exposure to 131 I in Childhood
…, A Bouville, G Goulko, M Hoshi… - Journal of the …, 2005 - academic.oup.com
Background: After the Chernobyl nuclear power plant accident in April 1986, a large increase
in the incidence of childhood thyroid cancer was reported in contaminated areas. Most of …
in the incidence of childhood thyroid cancer was reported in contaminated areas. Most of …
Aβ (1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease
…, S Parthasarathy, F Long, M Hoshi… - Nature structural & …, 2015 - nature.com
Increasing evidence has suggested that formation and propagation of misfolded aggregates
of 42-residue human amyloid β (Aβ(1–42)), rather than of the more abundant Aβ(1–40), …
of 42-residue human amyloid β (Aβ(1–42)), rather than of the more abundant Aβ(1–40), …
Spherical aggregates of β-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3β
M Hoshi, M Sato, S Matsumoto… - Proceedings of the …, 2003 - National Acad Sciences
β-Amyloid (Aβ) acquires toxicity by self-aggregation. To identify and characterize the toxic
form(s) of Aβ aggregates, we examined in vitro aggregation conditions by using large …
form(s) of Aβ aggregates, we examined in vitro aggregation conditions by using large …
[HTML][HTML] Remarkable role of indoleamine 2, 3-dioxygenase and tryptophan metabolites in infectious diseases: potential role in macrophage-mediated inflammatory …
Y Murakami, M Hoshi, Y Imamura, Y Arioka… - Mediators of …, 2013 - hindawi.com
Indoleamine 2,3-dioxygenase 1 (IDO1), the L-tryptophan-degrading enzyme, plays a key role
in the immunomodulatory effects on several types of immune cells. Originally known for its …
in the immunomodulatory effects on several types of immune cells. Originally known for its …
Exposure of rat hippocampal neurons to amyloid β peptide (25–35) induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I …
…, K Noguchi, G Michel, M Mercken, M Hoshi… - Neuroscience …, 1996 - Elsevier
… No PIP 3 production was observed in culture treated with 10 -6 M wortmannin or Aft (25-35)
(20/~M), suggesting that PI-3 kinase activity was completely inhibited under these conditions …
(20/~M), suggesting that PI-3 kinase activity was completely inhibited under these conditions …
Regulation of mitochondrial pyruvate dehydrogenase activity by tau protein kinase I/glycogen synthase kinase 3beta in brain.
M Hoshi, A Takashima, K Noguchi… - Proceedings of the …, 1996 - National Acad Sciences
According to the amyloid hypothesis for the pathogenesis of Alzheimer disease, beta-amyloid
peptide (betaA) directly affects neurons, leading to neurodegeneration and tau …
peptide (betaA) directly affects neurons, leading to neurodegeneration and tau …
Antioxidant activity of eugenol and related monomeric and dimeric compounds
M Ogata, M Hoshi, S Urano, T Endo - Chemical and Pharmaceutical …, 2000 - jstage.jst.go.jp
Materials and Methods Chemicals Caryophylli F [as was kindly supplied by Dr. T. Nishimura
of Teikyo University, Tokyo, Japan. Eugcnol was obtained from Tokyo Kasei Kogyo Co.(…
of Teikyo University, Tokyo, Japan. Eugcnol was obtained from Tokyo Kasei Kogyo Co.(…