User profiles for M. Schaaf
Marcel SchaafLeiden University Verified email at biology.leidenuniv.nl Cited by 6129 |
LC3/GABARAP family proteins: autophagy‐(un) related functions
MBE Schaaf, TG Keulers, MA Vooijs… - The FASEB …, 2016 - Wiley Online Library
From yeast to mammals, autophagy is an important mechanism for sustaining cellular
homeostasis through facilitating the degradation and recycling of aged and cytotoxic components. …
homeostasis through facilitating the degradation and recycling of aged and cytotoxic components. …
Molecular mechanisms of glucocorticoid action and resistance
MJM Schaaf, JA Cidlowski - The Journal of steroid biochemistry and …, 2002 - Elsevier
The actions of glucocorticoid hormones are mediated by an intracellular receptor, the
glucocorticoid receptor (GR). The mechanism of action of this ligand-inducible transcription factor …
glucocorticoid receptor (GR). The mechanism of action of this ligand-inducible transcription factor …
[HTML][HTML] Defining the role of the tumor vasculature in antitumor immunity and immunotherapy
MB Schaaf, AD Garg, P Agostinis - Cell death & disease, 2018 - nature.com
It is now well established that cancer cells co-exist within a complex environment with stromal
cells and depend for their growth and dissemination on tight and plastic interactions with …
cells and depend for their growth and dissemination on tight and plastic interactions with …
Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone
MJM Schaaf, J de Jong, ER de Kloet, E Vreugdenhil - Brain research, 1998 - Elsevier
Previously, we showed that corticosterone regulates BDNF mRNA levels in the hippocampus.
In the present study, we have investigated the time course and dose-dependency of this …
In the present study, we have investigated the time course and dose-dependency of this …
Corticosterone effects on BDNF expression in the hippocampus implications for memory formation
MJM Schaaf, ER De Kloet, E Vreugdenhil - Stress, 2000 - Taylor & Francis
… when administered to ADX animals (Schaaf et al., in press). However, after water maze
training, rats show increased BDNF mRNA expression in CAI at 1 hr after training (Schaaf et a]., …
training, rats show increased BDNF mRNA expression in CAI at 1 hr after training (Schaaf et a]., …
A 5000-yr record of climate change in varved sediments from the oxygen minimum zone off Pakistan, Northeastern Arabian Sea
U Von Rad, M Schaaf, KH Michels, H Schulz… - Quaternary …, 1999 - Elsevier
The upper Holocene marine section from a kasten core taken from the oxygen minimum
zone off Karachi (Pakistan) at water depth 700 m contains continuously laminated sediments …
zone off Karachi (Pakistan) at water depth 700 m contains continuously laminated sediments …
Glucocorticoid receptor variants: clinical implications
RH DeRijk, M Schaaf, ER De Kloet - The Journal of steroid biochemistry …, 2002 - Elsevier
Following exposure to stress, cortisol is secreted from the adrenal cortex under the control
of the hypothalamic-pituitary-adrenal axis (HPA-axis). Central in the regulation of the HPA-…
of the hypothalamic-pituitary-adrenal axis (HPA-axis). Central in the regulation of the HPA-…
A human glucocorticoid receptor gene variant that increases the stability of the glucocorticoid receptor beta-isoform mRNA is associated with rheumatoid arthritis.
RH Derijk, MJ Schaaf, G Turner, NA Datson… - The Journal of …, 2001 - jrheum.org
OBJECTIVE: To study the occurrence and function of polymorphism in the human glucocorticoid
receptor (hGR) gene in rheumatoid arthritis (RA) and systemic lupus erythematosus (…
receptor (hGR) gene in rheumatoid arthritis (RA) and systemic lupus erythematosus (…
Preoperative lateralization of ACTH-secreting pituitary microadenomas by bilateral and simultaneous inferior petrosal venous sinus sampling
…, GP Chrousos, HM Schulte, M Schaaf… - … England Journal of …, 1985 - Mass Medical Soc
PREVIOUS reports have established the utility of selective catheterization of the inferior
petrosal sinus for determination of plasma ACTH concentrations in the diagnosis of pituitary-…
petrosal sinus for determination of plasma ACTH concentrations in the diagnosis of pituitary-…
An affective disorder in zebrafish with mutation of the glucocorticoid receptor
… weeks CMS’); 50–90 min of 5 μM diazepam treatment (‘Diazepam 5 μM’); or 2 weeks of CMS
with 0.8 μM fluoxetine treatment (‘2 weeks CMS+Fluoxetine 0.8 μM’; n=3–9 fish per group; …
with 0.8 μM fluoxetine treatment (‘2 weeks CMS+Fluoxetine 0.8 μM’; n=3–9 fish per group; …