Background: There has been tremendous growth in research in pediatric multiple sclerosis (MS)
and immune mediated central nervous system demyelinating disorders since …

The onset of multiple sclerosis (MS) in childhood poses diagnostic and therapeutic challenges,
particularly if the symptoms of the first demyelinating event resemble acute disseminated …

HIV infection in brain revolves around productive viral replication in cells of mononuclear
phagocyte lineage, including brain macrophages, microglia, and multinucleated giant cells [1–4…

Some Toll and Toll-like receptors (TLRs) provide immunity to experimental infections in
animal models, but their contribution to host defense in natural ecosystems is unknown. We …

… to walk more than 500 m without aid or rest), 6 (ability to walk with unilateral support no more
than 100 m without rest), and 7 (ability to walk no more than 10 m without rest while using a …

Background Zidovudine is commonly administered during pregnancy to prevent mother-to-child
HIV-1 transmission. We investigated mitochondrial toxic effects in children exposed to …

Herpes simplex virus-1 (HSV-1) encephalitis (HSE) is the most common form of sporadic viral
encephalitis in western countries. Its pathogenesis remains unclear, as it affects otherwise …

… Some cultures were treated with the NOS inhibitor l-NAME (1 mm, Sigma) during anti-CD23
treatment. Cell-free supernatants were then collected to determine TNF-α and nitrite contents…

In the course of primary infection with herpes simplex virus 1 (HSV-1), children with inborn
errors of toll-like receptor 3 (TLR3) immunity are prone to HSV-1 encephalitis (HSE) 1 , 2 , 3 . …

… without aid or rest for more than 500 m) and 6 (ability to walk with unilateral support no more
than 100 … Suissa and M. Tardieu. The study was designed and supervised by G. Ponsot, C. …