There is an ongoing discussion whether ALS is primarily a disease of upper motor neurons
or lower motor neurons. We undertook a review to assess how new insights have contributed …

We previously linked Laing-type early-onset autosomal dominant distal myopathy (MPD1)
to a 22-cM region of chromosome 14. One candidate gene in the region, MYH7, which is …

… Drafting of the manuscript: van der Graaff, Westermann, and de Visser. Critical revision of …
intellectual content: van der Graaff, Grolman, Westermann, Boogaardt, Koelman, van der Kooi, …

… van der Graaff , … van der Graaff … van der Kooi for her help in recruiting patients and
Suzan Beyer for her assistance with preparing the figures. …

Background Treatment with one standard dose (2 g/kg) of intravenous immunoglobulin is
insufficient in a proportion of patients with severe Guillain-Barré syndrome. Worldwide, around …

One course of intravenous immunoglobulins (IVIg) of 2 g/kg is standard treatment in Guillain‐Barré
syndrome (GBS) patients unable to walk independently. Despite treatment some …

BACKGROUND AND PURPOSE: Upper motor neuron degeneration varies in different
phenotypes of MND. We used single-voxel MR spectroscopy of the primary motor cortex to detect …

Objective: To examine the effect of multidisciplinary ALS care on the quality-of-life (QoL) in
patients with ALS and their caregivers. Methods: In a cross-sectional study, 208 patients with …

… .nl), CBLM Majoie, MM van der Graaff, CA Grimbergen and FM … mm, scan matrix 70 x 112,
image matrix 128 x 128, slice thickness 2.2 mm, such that the voxel size was 2.0 x 2.0 x 2.2 mm…

… Because the left inferior oblique muscle paresis strongly suggested additional involvement
of the rostral mesencephalon, a second MRI scan with 3-mm slices to maximize resolution …