Metvan: a novel oxovanadium (IV) complex with broad spectrum anticancer activity
OJ D'Cruz, FM Uckun - Expert Opinion on Investigational Drugs, 2002 - Taylor & Francis
Among the 25 bis(cyclopentadienyl)vanadium(IV) and 14 oxovanadium(IV) compounds
synthesised and evaluated for anticancer activity, bis(4,7-dimethyl-1,10-phenanthroline) …
synthesised and evaluated for anticancer activity, bis(4,7-dimethyl-1,10-phenanthroline) …
Clinical development of microbicides for the prevention of HIV infection
OJ D'Cruz, FM Uckun - Current pharmaceutical design, 2004 - ingentaconnect.com
… While samples from groups O and N are limited to the African continent, with some isolated
cases of group O in Europe and in the United States, group M variants are responsible for the …
cases of group O in Europe and in the United States, group M variants are responsible for the …
Conversion to lacosamide monotherapy in the treatment of focal epilepsy: results from a historical‐controlled, multicenter, double‐blind study
Objective To evaluate the efficacy and safety of conversion to lacosamide 400 mg/day
monotherapy in adults with focal epilepsy. Methods This historical‐controlled, double‐blind study ( …
monotherapy in adults with focal epilepsy. Methods This historical‐controlled, double‐blind study ( …
Gel-microemulsions as vaginal spermicides and intravaginal drug delivery vehicles
OJ D'Cruz, FM Uckun - Contraception, 2001 - Elsevier
There is a need for novel formulations to improve the bioavailability through the vaginal/rectal
mucosa of microbicidal drug substances against sexually transmitted diseases. In addition, …
mucosa of microbicidal drug substances against sexually transmitted diseases. In addition, …
Bis (4, 7-dimethyl-1, 10-phenanthroline) sulfatooxovanadium (IV) as a novel apoptosis-inducing anticancer agent
RK Narla, Y Dong, OJ D'Cruz, C Navara… - Clinical cancer research, 2000 - AACR
In a systematic effort to identify a potent anticancer agent, we synthesized 15 oxovanadium(IV)
complexes and examined their cytotoxic activity against 14 different human cancer cell …
complexes and examined their cytotoxic activity against 14 different human cancer cell …
Efficacy of antiepileptic drugs in adults predicts efficacy in children: a systematic review
…, V Thyagarajan, T Daniels, DL Morris, ON D'Cruz - Neurology, 2012 - AAN Enterprises
… O. D'Cruz contributed to the design and conceptualization of the study, interpretation of
the data … D'Cruz is an employee of UCB Pharma, Raleigh, NC. Go to Neurology.org for full …
the data … D'Cruz is an employee of UCB Pharma, Raleigh, NC. Go to Neurology.org for full …
Distribution of human leukocyte antigen‐ABC and‐D/DR antigens in the unfixed human testis
GG HAAS JR, OJ D'CRUZ… - American journal of …, 1988 - Wiley Online Library
The distribution of the major histocompatibility complex (MHC) antigens in the unfixed human
testicle was studied by indirect immunofluorescence. Three murine monoclonal antibodies …
testicle was studied by indirect immunofluorescence. Three murine monoclonal antibodies …
Potent dual anti-HIV and spermicidal activities of novel oxovanadium (V) complexes with thiourea non-nucleoside inhibitors of HIV-1 reverse transcriptase
OJ D'Cruz, Y Dong, FM Uckun - Biochemical and biophysical research …, 2003 - Elsevier
We have previously demonstrated that tetrahedral bis(cyclopentadienyl)vanadium(IV)
complexes and square pyramidal oxovanadium(IV) complexes of vanadium are rapid and …
complexes and square pyramidal oxovanadium(IV) complexes of vanadium are rapid and …
Apoptosis-inducing vanadocene compounds against human testicular cancer
We systematically assessed the cytotoxic effects of five metallocene dichlorides containing
vanadium (vanadocene dichloride), titanium (titanocene dichloride), zirconium (zircodocene …
vanadium (vanadocene dichloride), titanium (titanocene dichloride), zirconium (zircodocene …
Dawn of non-nucleoside inhibitor-based anti-HIV microbicides
OJ D'Cruz, FM Uckun - Journal of Antimicrobial Chemotherapy, 2006 - academic.oup.com
The emergence of HIV/AIDS as a disease spread through sexual intercourse has prompted
the search for safe and effective vaginal and rectal microbicides for curbing mucosal viral …
the search for safe and effective vaginal and rectal microbicides for curbing mucosal viral …