The fourth edition of the World Health Organization (WHO) classification of tumours of the
central nervous system, published in 2007, lists several new entities, including angiocentric …

The 2016 World Health Organization Classification of Tumors of the Central Nervous System
is both a conceptual and practical advance over its 2007 predecessor. For the first time, the …

von Hippel-Lindau syndrome (HLS), an autosomal-dominant inherited disease, was studied
in 92 affected subjects from 29 kindreds. In an initial survey to identify HLS gene carriers, all …

Background 5-aminolevulinic acid is a non-fluorescent prodrug that leads to intracellular
accumulation of fluorescent porphyrins in malignant gliomas—a finding that is under …

Self-renewing, totipotent embryonic stem (ES) cells may provide a virtually unlimited donor
source for transplantation. A protocol that permits the in vitro generation of precursors for …

Purpose The standard of care for anaplastic gliomas is surgery followed by radiotherapy.
The NOA-04 phase III trial compared efficacy and safety of radiotherapy followed by …

The monoclonal antibody A60 specifically recognizes the DNA-binding, neuron-specific
protein NeuN, which is present in most neuronal cell types of vertebrates. In this study we …

Purpose: To describe the histologic spectrum and clinical characteristics of patients with
neuroepithelial tumors and drug‐resistant epilepsy and to analyze clinical data and treatment …

Sporadic, late-onset Alzheimer disease (AD) constitutes the most frequent cause of dementia
in the elderly population. AD-related pathology is often accompanied by vascular changes. …

The allele sizes of polymorphic microsatellite repeats in DNA from human cancers were
compared to normal DNA from the same patients. In 16 out of 196 paired samples (8%), we …