Effects of thyroid hormones on bone and mineral metabolism

L Mosekilde, EF Eriksen, P Charles - Endocrinology and metabolism clinics …, 1990 - Elsevier
Thyroid hormones exert major influences on bone and mineral metabolism. Hyperthyroidism
induces an accelerated bone loss and may thereby increase the risk of low-energy fractures…

Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor α

…, A Long‐Fox, P Charles, P Katsikis… - Arthritis & …, 1993 - Wiley Online Library
… 6 (P < 0.001), the swollen joint count, which fell from 18 to 5 (P < 0.001) over the same
period, and in the other major clinical assessments. Serum C‐reactive protein levels fell from a …

X10: an object-oriented approach to non-uniform cluster computing

P Charles, C Grothoff, V Saraswat, C Donawa… - Acm Sigplan …, 2005 - dl.acm.org
… If needed, standard point operations can be used to extract individual index values from
p eg, p[0] and p[1] return integer index values of the first and second dimensions of p. …

Alcaligenes eutrophus CH34 is a facultative chemolithotroph with plasmid-bound resistance to heavy metals

…, D Nies, HG Schlegel, J Gerits, P Charles… - Journal of …, 1985 - Am Soc Microbiol
Alcaligenes eutrophus strain CH34, which was isolated as a bacterium resistant to cobalt,
zinc, and cadmium ions, shares with A. eutrophus strain H16 the ability to grow …

Repeated therapy with monoclonal antibody to tumour necrosis factor α (cA2) in patients with rheumatoid arthritis

…, RN Maini, M Feldmann, A Long-Fox, P Charles… - The Lancet, 1994 - Elsevier
Our in-vitro, animal, and early clinical data suggest that tumour necrosis factor α (TNFα) is an
important target for specific biological therapy in rheumatoid arthritis. We report the results …

Hypovitaminosis D myopathy without biochemical signs of osteomalacic bone involvement

…, E Hass, S Overbeck, H Andersen, P Charles… - Calcified tissue …, 2000 - Springer
The aims of this study were to investigate myopathy in relation to vitamin D status, and to
study the muscular effects of vitamin D treatment on vitamin D-deficient individuals. Further, …

SMART-COP: a tool for predicting the need for intensive respiratory or vasopressor support in community-acquired pneumonia

PGP Charles, R Wolfe, M Whitby, MJ Fine… - Clinical infectious …, 2008 - academic.oup.com
… A backwards stepwise selection procedure was used with removal of variables that had P>.1
and reinclusion of variables that had P<.05. As a strategy to avoid overfitting, 1000 …

Commonly recommended daily intake of vitamin D is not sufficient if sunlight exposure is limited

…, S Overbeck, J Thomsen, P Charles… - Journal of internal …, 2000 - Wiley Online Library
… 160.5 ± 0.7 cm) and the body mass index (BMI) of the Arab women was slightly (P < 0.01) …
Arab women compared with 0% in Danish controls (P < 0.001). Muscle cramps were seen in 72…

Treatment Outcomes for Serious Infections Caused by Methicillin-Resistant Staphylococcus aureus with Reduced Vancomycin Susceptibility

BP Howden, PB Ward, PGP Charles… - Clinical Infectious …, 2004 - academic.oup.com
Although infections caused by methicillin-resistant Staphylococcus aureus with reduced
vancomycin susceptibility (SA-RVS) have been reported from a number of countries, including …

[HTML][HTML] Serum levels of IL-6 and TNF-α correlate with clinicopathological features and patient survival in patients with prostate cancer

V Michalaki, K Syrigos, P Charles, J Waxman - British journal of cancer, 2004 - nature.com
Interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-α) are important multifunctional
cytokines involved in tumour growth and metastasis. In this study, we have measured serial …