Inflammation and infections as risk factors for ischemic stroke

PJ Lindsberg, AJ Grau - Stroke, 2003 - Am Heart Assoc
Background— Inflammatory processes have fundamental roles in stroke in both the etiology
of ischemic cerebrovascular disease and the pathophysiology of cerebral ischemia. We …

Therapy of basilar artery occlusion: a systematic analysis comparing intra-arterial and intravenous thrombolysis

PJ Lindsberg, HP Mattle - Stroke, 2006 - Am Heart Assoc
Background and Purpose— Basilar artery occlusion (BAO) is an infrequent form of acute
stroke, which invariably leads to death or long-term disability if not recanalized. A traditional …

Basilar artery occlusion

HP Mattle, M Arnold, PJ Lindsberg… - The Lancet …, 2011 - thelancet.com
The clinical presentation of basilar artery occlusion (BAO) ranges from mild transient
symptoms to devastating strokes with high fatality and morbidity. Often, non-specific prodromal …

Treatment and outcomes of acute basilar artery occlusion in the Basilar Artery International Cooperation Study (BASICS): a prospective registry study

…, T Pfefferkorn, K Szabo, PJ Lindsberg… - The Lancet …, 2009 - thelancet.com
Background Treatment strategies for acute basilar artery occlusion (BAO) are based on
case series and data that have been extrapolated from stroke intervention trials in other …

Reducing in-hospital delay to 20 minutes in stroke thrombolysis

…, D Strbian, S Mustanoja, T Tatlisumak, PJ Lindsberg… - Neurology, 2012 - AAN Enterprises
Objectives: Efficacy of thrombolytic therapy for ischemic stroke decreases with time elapsed
from symptom onset. We analyzed the effect of interventions aimed to reduce treatment …

A candidate gene for developmental dyslexia encodes a nuclear tetratricopeptide repeat domain protein dynamically regulated in brain

…, K Muller, M Kaaranen, PJ Lindsberg… - Proceedings of the …, 2003 - National Acad Sciences
Approximately 3–10% of people have specific difficulties in reading, despite adequate
intelligence, education, and social environment. We report here the characterization of a gene, …

Nuclear factor-κB contributes to infarction after permanent focal ischemia

A Nurmi, PJ Lindsberg, M Koistinaho, W Zhang… - Stroke, 2004 - Am Heart Assoc
Background and Purpose— Activation of transcription factor nuclear factor-κB (NF-κB) may
induce expression of either proinflammatory/apoptotic genes or antiapoptotic genes. …

Endothelial ICAM-1 expression associated with inflammatory cell response in human ischemic stroke

PJ Lindsberg, O Carpe´ n, A Paetau… - Circulation, 1996 - Am Heart Assoc
Background After focal brain ischemia, leukocytes adhere to the perturbed endothelium and
are believed to aggravate reperfusion injury. Although ischemia-induced upregulation of …

Hyperglycemia in acute stroke

PJ Lindsberg, RO Roine - Stroke, 2004 - Am Heart Assoc
In several thrombolysis trials, hyperglycemia has been found to be associated with hemorrhagic
events16 and was reconfirmed recently17 as well as in a re-analysis of the NINDS rt-PA …

Evolution of cerebral tumor necrosis factor-α production during human ischemic stroke

…, A Paetau, U Turpeinen, M Kaste, PJ Lindsberg - Stroke, 2001 - Am Heart Assoc
Background and Purpose— Tumor necrosis factor-α (TNF-α) is detected in ischemic brain
cells in experimental animal models and is believed to play an important role in apoptosis. …