Cyclodextrins (CD) have been utilized extensively in pharmaceutical formulations to enhance
oral bioavailability. A critical review of the literature in which cyclodextrins were utilized for …

Highly automated systems are becoming omnipresent. They range in function from self-driving
vehicles to advanced medical diagnostics and afford many benefits. However, there are …

This literature review presents hydrolysis of active pharmaceutical ingredients as well as the
effects on dosage form stability due to hydrolysis of excipients. Mechanisms and …

The Functional Autonomy Measurement System (SMAF) is an instrument developed for the
measurement of the needs of the elderly and the handicapped. Its elaboration was based on …

Cardiac tissue engineering has been motivated by the need to create functional tissue
equivalents for scientific studies and cardiac tissue repair. We previously demonstrated that …

The objective of this study was to establish a three-dimensional (3-D) in vitro model system
of cardiac muscle for electrophysiological studies. Primary neonatal rat ventricular cells …

Microphysiological systems (MPSs) are in vitro models that capture facets of in vivo organ
function through use of specialized culture microenvironments, including 3D matrices and …

Cardiac muscle with a certain threshold thickness, uniformity of tissue architecture, and
functionality would expand the therapeutic options currently available to patients with congenital …

… gene carriers to target cells is often constrained by inefficient vector transport through complex
biological environments.1 Drug carriers … retard diffusion of a drug carrier or molecule.2, 6 …

Huntington's disease (HD) is a hereditary neurodegenerative disease that leads to striatal
degeneration and a severe movement disorder. We used a transgenic mouse model of HD (…