Since the original description by Taylor, the term focal cortical dysplasia has been used to
refer to a wide range of alterations of the cortical mantle. More recently, these conditions have …

Ongoing challenges in diagnosing focal cortical dysplasia (FCD) mandate continuous
research and consensus agreement to improve disease definition and classification. An …

Background Surgery is a widely accepted treatment option for drug-resistant focal epilepsy.
A detailed analysis of longitudinal postoperative seizure outcomes and use of antiepileptic …

We present the results of a retrospective study on 10 patients operated on for intractable
epilepsy associated with nodular heterotopia as identified by high resolution MRI. Seven …

Objective To alert about the wide margin of unpredictability that distribution of somatic MTOR
mosaicism may have in the brain and the risk for independent epileptogenesis arising from …

Pre-surgical and post-surgical data were examined and compared from 215 consecutive
patients undergoing surgery for intractable epilepsy. Patients were selected on the basis of a …

The present study included analysis of data from 243 patients surgically treated for Temporal
Lobe Epilepsy (TLE). Resection was confined to the temporal lobe, with at least two years …

Loss of myelin and altered oligodendrocyte distribution in the cerebral cortex are commonly
observed both in postsurgical tissue derived from different focal epilepsies (such as focal …

… studies have shown that BCs are not contacted by synaptic terminals (Garbelli … in a subset
of reactive astrocytes and BCs in specimens from patients with type IIb FCD (Garbelli et al., …

Objective Focal cortical dysplasia (FCD) is a major cause of difficult‐to‐treat epilepsy in
children and young adults, and the diagnosis is currently based on microscopic review of …