Purpose— Our goal is to provide an overview of the current evidence about components of
the evaluation and treatment of adults with acute ischemic stroke. The intended audience is …

Background and Purpose— This scientific statement provides an overview of the evidence
on vascular contributions to cognitive impairment and dementia. Vascular contributions to …

nally, the evaluation provides historical data or other information that can be used to establish
the vascular distribution of the stroke and to provide clues about its likely pathophysiology …

Despite the global impact and advances in understanding the pathophysiology of cerebrovascular
diseases, the term “stroke” is not consistently defined in clinical practice, in clinical …

… of intra-arterial (IA) recombinant prourokinase (r-proUK) in patients with acute stroke of less
… InterventionPatients were randomized to receive 9 mg of IA r-proUK plus heparin (n = 121) …

Purpose— The aim of this guideline is to present current and comprehensive recommendations
for the diagnosis and treatment of aneurysmal subarachnoid hemorrhage (aSAH). …

This scientific statement is intended for use by physicians and allied health personnel caring
for patients with transient ischemic attacks. Formal evidence review included a structured …

Background and Purpose— The only Food and Drug Administration (FDA)-approved treatment
for acute ischemic stroke is tissue plasminogen activator (tPA) given intravenously within …

Background and Purpose— Endovascular mechanical thrombectomy may be used during
acute ischemic stroke due to large vessel intracranial occlusion. First-generation MERCI …

… Therefore, on average, 7 patients with an MCA occlusion would require IA r-proUK for 1 to
benefit for the primary end point of achieving an mRSS ≤2 (mild or no disability). However, it …