Comparative analysis of phase I and II enzyme activities in 5 hepatic cell lines identifies Huh-7 and HCC-T cells with the highest potential to study drug metabolism

J Lin, L Schyschka, R Mühl-Benninghaus… - Archives of …, 2012 - Springer
Primary human hepatocytes (hHeps) are still gold standard to perform human drug metabolism
studies, but their availability is limited by donor organ scarcity. Therefore, hepatoma cell …

Spina bifida

R Mühl-Benninghaus - Der Radiologe, 2018 - Springer
Spina bifida bedeutet gespaltener Dornfortsatz oder einfach Spaltwirbel. Der Name wird als
Oberbegriff für die spinalen Dysraphien (griech.: Raphe = Naht) benutzt. Bei der Spina …

Acute occlusions of dual-layer carotid stents after endovascular emergency treatment of tandem lesions

U Yilmaz, H Körner, R Mühl-Benninghaus, A Simgen… - Stroke, 2017 - Am Heart Assoc
… Patients who were not administered IV r-tPA received a bolus of 5000 IU of heparin …
We did find a higher rate of stent occlusions when patients were not administered IV r-tPA, …

[HTML][HTML] Why we fail: mechanisms and co-factors of unsuccessful thrombectomy in acute ischemic stroke

…, P Dietrich, U Yilmaz, R Mühl-Benninghaus… - Neurological …, 2020 - Springer
Purpose Mechanical thrombectomy (MT) is an effective treatment for patients suffering from
acute ischemic stroke. However, recanalization fails in about 16.5% of interventions. We …

The Derivo embolization device, a second-generation flow diverter for the treatment of intracranial aneurysms, evaluated in an elastase-induced aneurysm model

D Ley, R Mühl-Benninghaus, U Yilmaz, H Körner… - Clinical …, 2017 - Springer
Purpose In recent years, flow diverters have provided a promising alternative to treat
complex intracranial aneurysms. In this study, we compare a second-generation flow-diverting …

Differential diagnostics of dementia type diseases

W Reith, R Mühl-Benninghaus - Der Radiologe, 2015 - Springer
Demenzen gehören zu den häufigsten neuropsychiatrischen Erkrankungen im höheren
Lebensalter und gehen mit erheblichen Belastungen für Betroffene und die Gesellschaft einher. …

Evaluation of a newly designed flow diverter for the treatment of intracranial aneurysms in an elastase-induced aneurysm model, in New Zealand white rabbits

…, C Roth, U Yilmaz, H Körner, R Mühl-Benninghaus… - Neuroradiology, 2014 - Springer
Introduction In this study, we analyzed angiographic and histologic aneurysm occlusion of a
newly designed flow-diverting device. Visibility and flexibility, as well as occlusions of side …

[HTML][HTML] The pCONUS HPC: 30-day and 180-day in vivo biocompatibility results

…, H Monstadt, A Simgen, R Mühl-Benninghaus… - CardioVascular and …, 2019 - Springer
… Ruben Mühl-Benninghaus MD received funding for the animal experiments from Phenox.
Wolfgang Reith MD, PhD, received funding for the animal experiments from Phenox. …

[HTML][HTML] Prospective study to assess the tissue response to HPC-coated p48 flow diverter stents compared to uncoated devices in the rabbit carotid artery model

…, H Monstadt, A Simgen, R Mühl-Benninghaus… - European Radiology …, 2019 - Springer
Background Flow diverters (FDs) are widely used in the treatment of intracranial aneurysms,
but the required medication increases the risk of haemorrhagic complications and limits …

Transient in-stent stenosis: a common finding after flow diverter implantation

R Mühl-Benninghaus, A Haußmann… - Journal of …, 2019 - jnis.bmj.com
Background and purpose In recent years, implantation of flow diverters has emerged as an
option for the endovascular treatment of intracranial aneurysms. One complication of …