Quantitative susceptibility mapping: technical considerations and clinical applications in neuroimaging

S Vinayagamani, R Sheelakumari… - Journal of Magnetic …, 2021 - Wiley Online Library
Quantitative susceptibility mapping (QSM) is a novel magnetic resonance imaging (MRI)
technique for quantifying the spatial distribution of magnetic susceptibility within an object or …

[HTML][HTML] A review of neuroimaging biomarkers of Alzheimer's disease

T Varghese, R Sheelakumari, JS James… - Neurology …, 2013 - ncbi.nlm.nih.gov
Neuroimaging biomarkers have potential role in the early diagnosis as well as periodic
follow-up of neurodegenerative diseases such as Alzheimer’s disease (AD). Structural imaging …

Neuroanatomical correlates of apathy and disinhibition in behavioural variant frontotemporal dementia

R Sheelakumari, C Bineesh, T Varghese… - Brain imaging and …, 2020 - Springer
Neuroanatomical correlates of apathy and disinhibition, behavioral abnormalities in behavioral
variant Frontotemporal dementia (bvFTD) remain unclear. In this study 45 participants (…

Regional cerebral blood flow in the posterior cingulate and precuneus and the entorhinal cortical atrophy score differentiate mild cognitive impairment and dementia …

B Thomas, R Sheelakumari… - American Journal …, 2019 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Alzheimer disease is the most common degenerative
dementia affecting humans and mild cognitive impairment is considered the forerunner of this …

[HTML][HTML] Construction of Indian human brain atlas

…, AJ Thottupattu, R Mehta, R Sheelakumari… - Neurology …, 2019 - journals.lww.com
Aims: The aim of this study is to construct and validate the Indian brain MRI atlas of young
Indian population and the corresponding structure probability maps. Settings and Design: This …

Assessment of iron deposition in the brain in frontotemporal dementia and its correlation with behavioral traits

R Sheelakumari, C Kesavadas… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Brain iron deposition has been implicated as a major
culprit in the pathophysiology of neurodegeneration. However, the quantitative assessment of …

A potential biomarker in amyotrophic lateral sclerosis: can assessment of brain iron deposition with SWI and corticospinal tract degeneration with DTI help?

R Sheelakumari, M Madhusoodanan… - American Journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Iron-mediated oxidative stress plays a pivotal role in the
pathogenesis of amyotrophic lateral sclerosis. This study aimed to assess iron deposition …

Quantitative analysis of grey matter degeneration in FTD patients using fractal dimension analysis

R Sheelakumari, V Rajagopalan, A Chandran… - Brain Imaging and …, 2018 - Springer
… (The box-counting method works by repeatedly applying different-sized meshes (r) to the
fractal image and counting the number of boxes (N) needed to completely cover the fractal). …

[HTML][HTML] Structural correlates of mild cognitive impairment: A clinicovolumetric study

R Sheelakumari, C Kesavadas, VS Lekha… - Neurology …, 2018 - journals.lww.com
Aims: To determine the structural differences between amnestic MCI and early AD using
volumetric magnetic resonance imaging (MRI) and its correlation with neuropsychological test …

[HTML][HTML] Multimodality neuroimaging in mild cognitive impairment: a cross-sectional comparison study

R Sheelakumari, SP Sarma, C Kesavadas… - Annals of Indian …, 2018 - journals.lww.com
Background and Purpose: Mild cognitive impairment (MCI) is a focus of considerable
research. The present study aimed to test the utility of a logistic regression-derived classifier, …