Delirium in elderly people

SK Inouye, RGJ Westendorp, JS Saczynski - The lancet, 2014 - thelancet.com
Delirium is an acute disorder of attention and cognition in elderly people (ie, those aged 65
years or older) that is common, serious, costly, under-recognised, and often fatal. A formal …

The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trials

…, SE Hoeks, AM Gotto, J Shepherd, RGJ Westendorp… - Bmj, 2009 - bmj.com
Objectives To investigate whether statins reduce all cause mortality and major coronary and
cerebrovascular events in people without established cardiovascular disease but with …

Subclinical hyperthyroidism and the risk of coronary heart disease and mortality

…, AB Newman, KT Khaw, RGJ Westendorp… - Archives of internal …, 2012 - jamanetwork.com
Background Data from prospective cohort studies regarding the association between subclinical
hyperthyroidism and cardiovascular outcomes are conflicting. We aimed to assess the …

Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials

…, PW Macfarlane, CJ Packard, DJ Stott, RG Westendorp… - The Lancet, 2010 - thelancet.com
Background Trials of statin therapy have had conflicting findings on the risk of development
of diabetes mellitus in patients given statins. We aimed to establish by a meta-analysis of …

Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial

…, DJ Stott, BJ Sweeney, G Twomey, RGJ Westendorp - The lancet, 2002 - thelancet.com
Background Although statins reduce coronary and cerebrovascular morbidity and mortality
in middle-aged individuals, their efficacy and safety in elderly people is not fully established. …

Subclinical hypothyroidism and the risk of coronary heart disease and mortality

…, AB Newman, J Cornuz, JA Franklyn, RGJ Westendorp… - Jama, 2010 - jamanetwork.com
Context Data regarding the association between subclinical hypothyroidism and cardiovascular
disease outcomes are conflicting among large prospective cohort studies. This might …

[HTML][HTML] HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

…, F Veglia, I Ford, JW Jukema, RGJ Westendorp… - The Lancet, 2015 - thelancet.com
Background Statins increase the risk of new-onset type 2 diabetes mellitus. We aimed to
assess whether this increase in risk is a consequence of inhibition of 3-hydroxy-3-methylglutaryl…

Thyroid status, disability and cognitive function, and survival in old age

…, AE Meinders, M Frölich, RGJ Westendorp - Jama, 2004 - jamanetwork.com
… Gussekloo, van Exel, de Craen, and Westendorp), Departments of General Internal Medicine
(… , inverse correlation at baseline between plasma levels of thyrotropin and free thyroxine (r

Genetic influence on cytokine production and fatal meningococcal disease

RGJ Westendorp, JAM Langermans, TWJ Huizinga… - The Lancet, 1997 - thelancet.com
… Differences between spouses in the production of TNF were not associated with the time
they lived together (r=0ˇ008, p=0ˇ95). Similar results were obtained for the production of IL-10 (r

Cellular origin and procoagulant properties of microparticles in meningococcal sepsis

…, FPH Th. M. Romijn, RGJ Westendorp… - Blood, The Journal …, 2000 - ashpublications.org
Patients with meningococcal sepsis generally suffer from disseminated intravascular
coagulation (DIC). The aim of this study was to address whether these patients have elevated …