… Ernst Russell Ernst received his BS in electrical engineering summa cum laude from the
University of Notre Dame in 2001, with a focus in control systems theory. After working as a …

Recent human decedent model studies 1 , 2 and compassionate xenograft use 3 have explored
the promise of porcine organs for human transplantation. To proceed to human studies, …

Identifying the proteins synthesized at specific times in cells of interest in an animal will
facilitate the study of cellular functions and dynamic processes. Here we introduce stochastic …

Genetically encoded unnatural amino acids provide powerful strategies for modulating the
molecular functions of proteins in mammalian cells. However, this approach has not been …

Site-specific incorporation of non-natural amino acids into proteins, via genetic code
expansion with pyrrolysyl tRNA synthetase (PylRS) and tRNA Pyl CUA pairs (and their evolved …

Powerful SIMD instructions in modern processors offer an opportunity for greater search
performance. In this paper, we apply these instructions to decoding search engine posting lists. …

We develop an approach to tag proteomes synthesized by specific cell types in dissociated
cortex, brain slices, and the brains of live mice. By viral-mediated expression of an …

The ability to assign cellular origin to low-abundance secreted factors in extracellular vesicles
(EVs) would greatly facilitate the analysis of paracrine-mediated signaling. Here, we report …

Mismatches in DNA occur naturally during replication and as a result of endogenous DNA
damaging agents, but the mismatch repair (MMR) pathway acts to correct mismatches before …

Mismatch repair (MMR) is critical to maintaining the integrity of the genome, and deficiencies
in MMR are correlated with cancerous transformations. Bulky rhodium intercalators target …