The nine SLAM‐family genes, SLAMF1–9, a subfamily of the immunoglobulin superfamily,
encode differentially expressed cell‐surface receptors of hematopoietic cells. Engagement …

Objective To answer the following research question: “Dolow/medium hydrogen peroxide (HP)
concentrations used for in-office bleaching in patients with permanent dentition have …

Limited proteolysis of gasdermin D (GSDMD) generates an N-terminal pore-forming
fragment that controls pyroptosis in macrophages. GSDMD is processed via inflammasome-…

Receptor-interacting protein kinase 3 (RIP3 or RIPK3) has emerged as a central player in
necroptosis and a potential target to control inflammatory disease. Here, three selective small-…

RIP1 regulates necroptosis and inflammation and may play an important role in contributing
to a variety of human pathologies, including immune-mediated inflammatory diseases. Small…

… blockade of RIP1 kinase activity with Nec-1, because compounds with better potency and
pharmacokinetics can completely block TNF and zVAD–induced temperature loss (SB Berger, …

Receptor interacting protein kinase 1 (RIPK1) has an essential role in the signalling triggered
by death receptors and pattern recognition receptors 1 , 2 . RIPK1 is believed to function as …

The pronecrotic kinase, receptor interacting protein (RIP1, also called RIPK1) mediates
programmed necrosis and, together with its partner, RIP3 (RIPK3), drives midgestational death of …

The recent discovery of the role of receptor interacting protein 1 (RIP1) kinase in tumor
necrosis factor (TNF)-mediated inflammation has led to its emergence as a highly promising …

Phagocytosis is a pivotal process by which macrophages eliminate microorganisms after
recognition by pathogen sensors. Here we unexpectedly found that the self ligand and cell …