A locus control region adjacent to the human red and green visual pigment genes
Y Wang, JP Macke, SL Merbs, DJ Zack, B Klaunberg… - Neuron, 1992 - cell.com
Deletion of sequences 5’of the human red and green pigment gene array results in blue cone
monochromacy, a disorder in which both red and green cone function are absent. To test …
monochromacy, a disorder in which both red and green cone function are absent. To test …
Absorption spectra of human cone pigments
SL Merbs, J Nathans - Nature, 1992 - nature.com
HUMAN colour vision is mediated by three light-sensitive pigments, each found in a different
cone-cell type 1 . The absorption spectra of the human cone pigments have been sought for …
cone-cell type 1 . The absorption spectra of the human cone pigments have been sought for …
Use of porous polyethylene with embedded titanium in orbital reconstruction: a review of 106 patients
…, NT Iliff, MP Grant, SL Merbs - Ophthalmic Plastic & …, 2007 - journals.lww.com
Purpose: To evaluate our initial experience with a porous polyethylene implant with
embedded titanium in orbital reconstruction. Methods: A retrospective review of the charts was …
embedded titanium in orbital reconstruction. Methods: A retrospective review of the charts was …
Melanopsin signalling in mammalian iris and retina
Non-mammalian vertebrates have an intrinsically photosensitive iris and thus a local pupillary
light reflex (PLR). In contrast, it is thought that the PLR in mammals generally requires …
light reflex (PLR). In contrast, it is thought that the PLR in mammals generally requires …
Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death
Glaucoma, a major cause of blindness worldwide, is a neurodegenerative optic neuropathy
in which vision loss is caused by loss of retinal ganglion cells (RGCs). To better define the …
in which vision loss is caused by loss of retinal ganglion cells (RGCs). To better define the …
Molecular genetics of human visual pigments
J Nathans, SL Merbs, CH Sung… - Annual review of …, 1992 - annualreviews.org
Human vision is based upon four light-sensitive pigments: in dim light, it is mediated by
rhodopsin, the visual pigment in rod photoreceptors, and at higher light levels, it is mediated by …
rhodopsin, the visual pigment in rod photoreceptors, and at higher light levels, it is mediated by …
Absorption spectra of the hybrid pigments responsible for anomalous color vision
SL Merbs, J Nathans - Science, 1992 - science.org
Unequal homologous recombination events between green and red cone pigment genes
produce the red-green or green-red hybrid pigment genes found in many individuals with …
produce the red-green or green-red hybrid pigment genes found in many individuals with …
[HTML][HTML] Characterization of tissue-specific differential DNA methylation suggests distinct modes of positive and negative gene expression regulation
Background DNA methylation plays an important role in regulating gene expression during
many biological processes. However, the mechanism of DNA-methylation-dependent gene …
many biological processes. However, the mechanism of DNA-methylation-dependent gene …
[HTML][HTML] ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration
Age-related macular degeneration (AMD) is a significant cause of vision loss in the elderly.
The extent to which epigenetic changes regulate AMD progression is unclear. Here we …
The extent to which epigenetic changes regulate AMD progression is unclear. Here we …
Allelotype of posterior uveal melanoma: implications for a bifurcated tumor progression pathway
P Parrella, D Sidransky, SL Merbs - Cancer research, 1999 - AACR
To further elucidate the somatic genetic alterations leading to acquired choroidal and
ciliochoroidal melanoma, we screened every autosomal arm and the X chromosome of 50 primary …
ciliochoroidal melanoma, we screened every autosomal arm and the X chromosome of 50 primary …